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PedAM

Pediatric Disease Annotations & Medicines




Disease colorectal cancer
Phenotype C0028754|obesity
Sentences 26
PubMedID- 26366838 Is obesity an advantage in patients with colorectal cancer.
PubMedID- 24127414 Conclusions: this population-based study confirms previous findings of increased risk of mss colorectal cancer with obesity between both sexes and suggests that overweight and obesity may also be associated with increased risk of msi-high colorectal cancer among women.
PubMedID- 22799628 Besides the association between obesity and occurrence of colorectal cancer [8], the safety, feasibility, short-term outcomes and oncologic effectiveness of this approach could be affected by obesity.
PubMedID- 24069323 In addition, an increased risk of colorectal cancer was associated with obesity in men (hr: 1.18, 95% ci: 1.11, 1.26), but not in women (hr: 1.06, 95% ci: 0.96, 1.17).
PubMedID- 23072404 Background: it remains unclear whether the increased risk of colorectal cancer (crc) associated with obesity differs by gender, distribution of fat, tumour location and clinical (tnm) stage.
PubMedID- 21734388 Energy consumption also influences colorectal cancer risk, with obesity increasing risk and exercise reducing risk.
PubMedID- 21709286 Breast and colorectal cancers are particularly associated with obesity and insulin resistance.
PubMedID- 25811460 Pre-diagnosis obesity was significantly associated with increased colorectal cancer-specific mortality (rr: 1.22, 95% ci: 1.003–1.35, p < 0.01) and all-cause mortality (rr: 1.25, 95% ci: 1.14–1.36, p < 0.01).
PubMedID- 26467912 While many epidemiology studies have shown that obesity increases the risk of developing colorectal cancer, there has been conflicting data on the prognostic impact of obesity in stage ii and iii colorectal cancer patients [10–15].
PubMedID- 23136317 Background: obesity increases the risk of many cancers including colorectal cancer (crc).
PubMedID- 22289950 In addition, obesity in patients with colorectal cancer negatively affects the disease progression and response of chemotherapy.
PubMedID- 22907422 Numerous observational studies have reported associations between obesity and risk of cra or colorectal cancer (crc), with variable reporting of obesity-associated risks based on gender, colorectal subsite, and adenoma characteristics (e.g., number, size, histology, and high-risk features) [4–9].
PubMedID- 23790994 Background: delivering personal narratives and peer support for crc screening in an online weight-loss community could be an efficient approach to engaging individuals at increased risk, because obesity is associated with excess colorectal cancer (crc) mortality and lower screening rates.
PubMedID- 22102975 For obesity, the relative risks of colorectal cancer were high, being 1.5-2.0 and 1.2-1.5 in males and females, respectively, and a similar relation was found in colorectal adenomas.
PubMedID- 22511581 Adipokines linking obesity with colorectal cancer risk in postmenopausal women.
PubMedID- 23405123 It has been well established that obesity influences the incidence of colorectal cancer [6], [7].
PubMedID- 24663336 Background: observational studies have consistently associated obesity with colorectal cancer risk.
PubMedID- 22511254 Risk alleles for two obesity snps were associated with colorectal cancer risk--kctd15 rs29941 [odds ratio (or) for c allele = 0.90, 95% confidence interval (ci) 0.83-0.98; p = 0.01] and mc4r rs17782313 (or for c allele = 1.12, 95% ci 1.02-1.22; p = 0.02).
PubMedID- 22357207 Epidemiological studies have indicated that obesity is associated with colorectal cancer.
PubMedID- 24119458 Conclusion: there was no significant correlation between obesity and outcomes of patients with colorectal cancer.
PubMedID- 24369529 In the joint who and fao report from 2003 experts have concluded that there is sufficient evidence that overweight and obesity increases the risk of colorectal cancer [7].
PubMedID- 23259085 Thus despite the chronological link between the onset of an and the diagnosis of cancer, it is difficult to conclude if this patient truly had malignant an, or obesity-associated an with coincidental colorectal cancer, especially as there is no difference in the histopathological findings between the two.
PubMedID- 24946743 Is obesity associated with colorectal cancer screening for african american and latino individuals in the context of patient navigation.
PubMedID- 23304125 Two large prospective cohort studies have shown that obesity increases the risk of colorectal cancer by approximately 1.5-fold compared with normal weight individuals (bmi 18.5–24.9 kg/m2) [95, 96].
PubMedID- PMC4070608 obesity and risk of colorectal cancer: a meta-analysis.
PubMedID- 23276970 This review outlines the association of obesity with risk of colorectal cancer and the potential underlying mechanisms from an epidemiological perspective.

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