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PedAM

Pediatric Disease Annotations & Medicines




Disease colorectal cancer
Phenotype C0015230|rash
Sentences 4
PubMedID- 24332355 Pilot clinical trial on the efficacy of prophylactic use of vitamin k1-based cream (vigorskin) to prevent cetuximab-induced skin rash in patients with metastatic colorectal cancer.
PubMedID- 23855804 Interestingly, almost all studies addressing egfr-inhibitor-induced skin rash done in patients with metastatic colorectal cancer suggest that its severity is a suitable surrogate marker for efficacy of anti-egfr therapy [44-47].
PubMedID- 23321777 The objective of this review is to assess the predictive value of skin rash in patients with advanced colorectal cancer treated with cetuximab and panitumumab.
PubMedID- 23238388 Conclusions: the prophylactic application of topical vitamin k1 cream did not translate into clinically meaningful benefit in terms of reducing acneiform rash in patients with metastatic colorectal cancer treated with cetuximab.

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