PedAM
Pediatric Disease Annotations & Medicines
| Disease | colorectal cancer |
| Phenotype | C0011847|diabetes |
| Sentences | 32 |
| PubMedID- 26307605 | Conclusions: acarbose use reduced the risk of incident colorectal cancer in patients with diabetes in a dose-dependent manner. |
| PubMedID- 20531412 | The association of diabetes with colorectal cancer risk: the multiethnic cohort. |
| PubMedID- 26331456 | This study aimed to investigate whether colorectal cancer patients with type 2 diabetes who were exposed to metformin had reduced cancer-specific mortality. |
| PubMedID- 24069323 | We constructed age-adjusted cox proportional hazard models to estimate the hazard ratio (hr) and corresponding 95% confidence intervals (ci) of incident colorectal cancer associated with history of diabetes at baseline. |
| PubMedID- 23043163 | In our additional analysis, the association between the use of low-dose aspirin or nsaids and the decreased risk of colorectal cancer in patients with diabetes was consistent with prior studies. |
| PubMedID- 21913184 | The effects of metformin on the survival of colorectal cancer patients with diabetes mellitus. |
| PubMedID- 25252097 | The dosage, frequency and duration of aspirin use that are sufficient to prevent the incidence of colorectal cancer in people with diabetes require further study. |
| PubMedID- 24507584 | colorectal cancer (crc) patients with pre-existing diabetes have significantly lower rates of overall survival compared with patients without diabetes. |
| PubMedID- 24569466 | However, diabetes was not associated with increased colorectal cancer-specific mortality after accounting for non-colorectal cancer outcomes as competing risk. |
| PubMedID- 23966577 | The use of metformin and colorectal cancer incidence in patients with type ii diabetes mellitus. |
| PubMedID- 24042261 | Methods: we conducted a systematic search of multiple bibliographic databases, up to september 2012, for articles that evaluated exposure to metformin, tzd, sulfonylureas, and insulin, reported colorectal cancer risk in patients with diabetes mellitus, and reported or or provided data for their estimation. |
| PubMedID- 22526616 | However, the authors’ overall conclusion was that much of the long-term mortality risk in colorectal cancer patients with diabetes can be attributed to causes other than cancer. |
| PubMedID- 22053841 | Results: there was an increase in the rr of developing colorectal cancer in persons with diabetes compared with those without diabetes (rr 1.28 [95%ci 1.19 - 1.39]), without heterogeneity between studies (p(heterogeneity) = .13). |
| PubMedID- 25535499 | Prevalence of hypertension and type 2 diabetes mellitus in patients with colorectal cancer and their median survival time: a cohort study. |
| PubMedID- 22203527 | Although little is known about the effect of metformin on human colorectal carcinogenesis, recent epidemiological studies have shown reduced incidence of colorectal cancer in patients with type 2 diabetes taking metformin when compared with those patients who do not take metformin [20, 23-25]. |
| PubMedID- 24864247 | A recent meta-analysis of 23 articles demonstrated a 41% increase in cancer mortality related to endometrial, breast, and colorectal cancers in patients with preexisting diabetes compared with normoglycemic individuals [21]. |
| PubMedID- 21602532 | The association of diabetes status with colorectal cancer risk was somewhat weakened after adjustment for these snps. |
| PubMedID- 24073162 | Because diabetes is associated with increased colorectal cancer (crc) risk, it is important that people with diabetes receive crc screenings according to guidelines. |
| PubMedID- 23304464 | Overall findings of diabetes association with colorectal cancer have not been entirely consistent [51]. |
| PubMedID- 25552419 | Objective: to assess the risk of colorectal cancer associated with type 2 diabetes, as compared with a nondiabetic reference population, and to study additional associations between treatment stage and duration of obesity and colorectal cancer risk. |
| PubMedID- 24334910 | colorectal cancer is associated with diabetes mellitus and both of these common conditions are often managed together by a surgeon. |
| PubMedID- 21442483 | Objective: to evaluate the association of diabetes mellitus(dm) with colorectal cancer. |
| PubMedID- 25038764 | Purpose: non-metastatic colorectal cancer patients with diabetes have poor overall survival than those without diabetes. |
| PubMedID- 21773024 | A recent meta-analysis of 23 articles indicated a 41% increase in cancer mortality related to endometrial, breast, and colorectal cancer in patients with preexisting diabetes as compared to normoglycemic individuals [21]. |
| PubMedID- 23396857 | A plausible support for the hypothesis that hyperinsulinemia may play a role in colorectal carcinogenesis comes from observational studies that found a higher risk of colorectal cancer in individuals with type 2 diabetes mellitus, which is usually associated with hyperinsulinemia, compared with individuals without diabetes. |
| PubMedID- 23242018 | However, the effect of metformin in stage iv colorectal cancer (crc) patients with diabetes mellitus (dm) remains unknown. |
| PubMedID- 21221236 | For instance, in patients undergoing colorectal cancer surgery, those with diabetes had a 23% lower in hospital mortality and fewer postoperative complications compared to those without diabetics [3], but the reason for this finding is uncertain. |
| PubMedID- 23151022 | colorectal cancer patients with diabetes treated with metformin as part of their diabetic therapy appeared to have a superior overall survival rate [16]. |
| PubMedID- 20352362 | Conclusions: in patients undergoing colorectal cancer surgery, those with diabetes had a 23% lower mortality and fewer postoperative complications compared to non-diabetics. |
| PubMedID- 20383575 | diabetes and risk of incident colorectal cancer in a prospective cohort of women. |
| PubMedID- 24685092 | [clinicopathological characteristics of colorectal cancer complicated with type 2 diabetes mellitus: analysis of clinicopathological data from 3, 202 colorectal cancer patients]. |
| PubMedID- 20351229 | (13) evaluated the risk of 30-day mortality in 32,621 colorectal cancer patients with and without diabetes from the veteran's affairs database. |
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