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PedAM

Pediatric Disease Annotations & Medicines




Disease colorectal cancer
Phenotype C0001430|adenoma
Sentences 8
PubMedID- 20461763 adenoma incidence after resection of sporadic colorectal cancer with microsatellite instability.
PubMedID- 21706233 Promoter methylation status of hmlh1, hmsh2, and mgmt genes in colorectal cancer associated with adenoma-carcinoma sequence.
PubMedID- 20370730 Male sex and current smoking habits along with a family history of colorectal cancer were associated with advanced adenoma in this age group.
PubMedID- 24355609 The adenoma-carcinoma sequence of colorectal cancers (crcs), defined histopathologically, has been postulated to occur as the consequence of an ordered series of mutations in a limited set of cancer genes (e.g.
PubMedID- 26118574 Results showed a low voluntary participation rate (17%), acceptable overall adenoma detection rate of 20,5% and colorectal cancer interval rate of 5,4%.
PubMedID- 21575164 It has been suggested that somatic mutations accumulate with age and appear in adenoma, the precursor of colorectal cancer [4], but the mechanism for this still needs to be clarified in future research.
PubMedID- 24765303 The etiology of the cancer is similar to those of the rest of the colon.1 the etiology of colorectal cancer include, adenoma carcinoma sequence, environmental factors (dietary red meat, animal fat and lower fiber diet), heredity cases, polyposis syndrome, lynch syndrome, chronic inflammatory disease like ulcerative colitis and crohn’s disease.8 these risk factors which are well established in the developed countries may be similar to risk factors in the developing countries.2,9 in the second case, the colonoscopy was able to visualize adenoma in the descending colon.
PubMedID- 25884547 Among the 194 iras colon study participants included in this analysis, older men who had previously reported being screened for colorectal cancer were significantly associated with adenoma prevalence in the bivariate analysis (table 1).

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