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PedAM

Pediatric Disease Annotations & Medicines




Disease collagen disease
Phenotype C0024115|lung disease
Sentences 25
PubMedID- 26424433 The human ethics review committee of kagoshima university school of medicine approved the study protocol and all participants provided written informed consent prior to enrolment in the study.table 1characteristics of patients with interstitial lung disease associated with connective tissue disease (ctd-ild), undifferentiated ctd-ild (uctd-ild), chronic fibrosing interstitial lung disease (cfip), and control subjectscontrolcfipuctd-ildctd-ildp-valuesubjects, n26191633age, years64 (59–81)67 (54–80)70 (53–79)63 (39–83)0.0265females, n (%)16 (61)3 (15)8 (50)22 (66)0.0032smoking status former smoker, n (%)7 (26)12 (63)8 (50)11 (33)0.0617 current smoker, n (%)1 (3)2 (10)1 (6)0 (0)0.3250 pack-years0 (0–40)30 (0–150)5 (0–70)0 (0–100)0.0035pa, o2 mmhg83.6 (62.4–111.7)72.5 (58.8–86.6)79.2 (42.3–105.2)0.1413kl-6, u · ml−1261 (140–491)1581 (304–8298)1045 (363–4560)1117 (289–3943)<0.0001sp-d, ng · ml−132.3 (8.6–126.0)292.5 (32.3–1070)206.0 (88.6–405)175.0 (31.2–994.0)<0.0001baff, ng · ml−10.6 (0.5–0.9)1.0 (0.3–1.9)1.8 (1.0–2.3)2.0 (0.6–16.7)<0.0001vc, l1.9 (0.9–3.1)2.1 (0.9–3.1)2.0 (1.0–3.5)0.9213vc, % pred59.8 (35.4–128.2)69.2 (37.9–97.4)65.4 (41.3–104.1)0.3390dl,co, ml · min−1 · mmhg−19.3 (3.4–15.4)8.9 (4.5–16.9)10.8 (4.6–16.9)0.6097dl,co, %pred63.2 (43.5–125.4)60.4 (26.9–74.4)64.7 (29.0–109.4)0.2751data are presented as counts (n) or medians and ranges (minimum-to-maximum values), unless otherwise stated.
PubMedID- 23683373 The frequency of lung disease associated with collagen diseases is on the rise.
PubMedID- 21597375 Purpose of review: there is no specific therapy for interstitial lung disease associated with connective tissue diseases (ctds-ild), a potentially fatal condition for some of these patients.
PubMedID- 22818583 connective tissue diseases are often associated with lung diseases that lead to high morbidity and mortality, including interstitial disease, airway disease, pleural lesions, and vascular disease.
PubMedID- 22967460 In a retrospective cohort study of patients with progressive interstitial lung disease (ild) associated with connective tissue disease not responding to conventional immunosuppressive regimens, rituximab improved lung function in seven of eight patients [24].
PubMedID- 26491278 Distribution according to pulmonary diseases was 48.0% (47/98) copd, including 15 acute stage and 32 stable stage of copd; 25.5% (25/98) ilds, including five idiopathic pulmonary fibrosis, five fibro-sing lung disease associated with connective tissue disease, three sarcoidosis, eight cryptogenic organizing pneumonia, and four diffuse alveolar hemorrhage; 18.4% (18/98) cf and 8.2% (8/98) cb (table 2).
PubMedID- 22781207 Summary: the syndrome of cpfe is a distinct pulmonary manifestation in the spectrum of lung diseases associated with connective tissue diseases, especially in smokers or ex-smokers.
PubMedID- 23289473 [interstitial lung disease associated with connective tissue diseases: diagnosis and treatment approaches].
PubMedID- 25972968 Lung-dominant connective tissue disease among patients with interstitial lung disease: prevalence, functional stability, and common extrathoracic features.
PubMedID- 24023556 Among them, idiopathic pulmonary fibrosis and connective tissue disease-associated interstitial lung disease are specific categories that pulmonologists are most likely to encounter in the clinical field.
PubMedID- 21437858 For example, the nsip pattern is most commonly found in interstitial lung disease due to connective tissue disease.
PubMedID- 26327779 Autoantibody profiles in collagen disease patients with interstitial lung disease (ild): antibodies to major histocompatibility complex class i-related chain a (mica) as markers of ild.
PubMedID- 24171031 Our study compared the prevalence and characteristics of patients with connective tissue disease-associated interstitial lung disease (ctd-ild), undifferentiated connective tissue disease-associated interstitial lung disease (uctd-ild), or idiopathic pulmonary fibrosis (ipf) between january 2009 and december 2012 in west china hospital, western china.
PubMedID- 22282550 In very severe interstitial lung disease associated with connective tissue disease (ctd-ild), progressing despite maximal conventional immunosuppression, there is no effective medical rescue therapy.
PubMedID- 20936629 Objective: connective tissue diseases (ctds) are associated with several interstitial lung diseases.
PubMedID- 25995034 Objective: to examine clinical utility of 18f-flurodeoxyglucose (fdg)-positron emission tomography (pet)/ct for assessment of interstitial lung disease (ild) in patients with connective tissue diseases (ctds).
PubMedID- 24003680 In the later course of the disease clinical picture of mixed connective tissue disease associated with interstitial lung disease, with a dominant picture of systemic sclerosis have emerged.
PubMedID- 22390563 Treatment of interstitial lung diseases associated with connective tissue diseases.
PubMedID- 24438527 Other competing diagnoses like infections, carcinomas, idiopathic interstitial pneumonia or interstitial lung diseases associated with a rheumatic disease have to be excluded.
PubMedID- 24252051 Increased serum concentration of baff/april and iga2 subclass in patients with mixed connective tissue disease complicated by interstitial lung disease.
PubMedID- 21285162 An analysis of connective tissue disease-associated interstitial lung disease at a us tertiary care center: better survival in patients with systemic sclerosis.
PubMedID- 20069430 Undifferentiated connective tissue disease-associated interstitial lung disease: changes in lung function.
PubMedID- 23457161 Interstitial lung disease associated with connective tissue disease has been definitely established to have a better long-term survival than ipf.
PubMedID- 21645423 Undifferentiated connective tissue disease presenting with prevalent interstitial lung disease: case report and review of literature.
PubMedID- 26443305 Yamamoto has investigated the association between connective tissue disease with interstitial lung disease and tumour maker ca19–9, and found that ild increased as the expression of ca19–9 increased and that the level of ca19–9 was inversely related with dlco25.

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