PedAM
Pediatric Disease Annotations & Medicines
| Disease | colitis |
| Phenotype | C0021400|influenza |
| Sentences | 2 |
| PubMedID- 24453980 | In order to investigate the role of trem-1 in homeostasis and disease, we have generated a trem-1-deficient (trem1−/−) mouse by targeted deletion of exon 2. here we show, employing distinct inflammation and infection models ranging from experimental colitis to infections with leishmania major, influenza virus and legionella pneumophila, that complete absence of trem-1 significantly attenuates morbidity and immune-mediated pathologies while microbial control remains unimpaired. |
| PubMedID- 25706391 | [36] reported a case of hemorrhagic colitis after infection with seasonal influenza a h3n2 virus. |
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