PedAM
Pediatric Disease Annotations & Medicines
| Disease | colitis |
| Phenotype | C0009402|colorectal cancer |
| Sentences | 27 |
| PubMedID- 23435402 | Five-year mortality in colorectal cancer patients with ulcerative colitis or crohn's disease: a nationwide population-based cohort study. |
| PubMedID- 25649787 | A retrospective dutch nationwide population-based analysis found that approximately 20% of colorectal cancer cases in patients with ulcerative colitis presented prior to the recommended initiation of screening colonoscopy [8]. |
| PubMedID- 21404516 | colorectal cancer, in patients with ulcerative colitis, is detected in the resected tissue of approximately 5% of patients, according to the literature. |
| PubMedID- 20656250 | The incidence of colorectal cancer associated with ulcerative colitis (uc) increases with time. |
| PubMedID- 23867875 | Methylated eyes absent 4 (eya4) gene promotor in non-neoplastic mucosa of ulcerative colitis patients with colorectal cancer: evidence for a field effect. |
| PubMedID- 23446340 | The risk of colorectal cancer in patients with long-standing ulcerative colitis or colonic crohn's disease is increased. |
| PubMedID- 25029614 | colorectal cancer associated with chronic colitis arises from dysplasia. |
| PubMedID- 24766737 | The pathogenesis of colorectal cancer in patients with ulcerative colitis is triggered by inflammation-dependent mechanisms [4]. |
| PubMedID- 21618350 | Background: chronic ulcerative colitis (uc) is associated with an increased colorectal cancer risk which may be secondary to repetitive mucosal injury. |
| PubMedID- 25412264 | Nuclear factor-kappa b (nf-kappab) is an important molecule in mediating inflammatory colitis, which can lead to colorectal cancer (crc). |
| PubMedID- 22552273 | Dysplasia and colorectal cancer in a patient with ulcerative colitis and primary sclerosing cholangitis: a case report and a short review of the literature. |
| PubMedID- 21859497 | Importantly, it has been reported that the administration of 0.6% curcumin in the diet prevented the progression of colorectal cancer associated with colitis in c57bl/6 mice by inhibiting the translocation of β-catenin from adherens junction complexes to the cytoplasm and nucleus and reducing the levels of diverse proinflammatory cytokines, inducible nitric oxide synthase (inos) and cox-2 as compared to untreated mice (figure 1) [167]. |
| PubMedID- 25437823 | The incidence of dysplasia and colorectal cancer in patients with long-standing colitis seems to be decreasing and controversy surrounds our detection and management strategies. |
| PubMedID- 21979184 | Increased risk of colorectal cancer and dysplasia in patients with crohn's colitis and primary sclerosing cholangitis. |
| PubMedID- 25834332 | Aim: to determine the incidence and risk factors for colorectal cancer (crc) in patients with ulcerative colitis from a low prevalence region for crc. |
| PubMedID- 21425209 | Myeloperoxidase immunohistochemistry as a measure of disease activity in ulcerative colitis: association with ulcerative colitis-colorectal cancer, tumor necrosis factor polymorphism and runx3 methylation. |
| PubMedID- 21468069 | Whether or not 5-aminosalicylates can prevent colorectal cancer among patients with colitis remains an open question. |
| PubMedID- 23118901 | Inflammation plays a crucial role in the cancer development [4], and chronic inflammation leading to inflammatory bowel disease (crohn's disease and ulcerative colitis) is associated with colorectal cancer risk [5]. |
| PubMedID- 22104750 | The colorectal cancer risks of ulcerative colitis and crohn's disease with comparable surface area involvement and disease duration are very similar. |
| PubMedID- 25981516 | Psc is a premalignant condition, associated with higher rates of hepatobiliary and colorectal cancer in patients with ulcerative colitis (uc). |
| PubMedID- 22312529 | [17] reported good clinical results with laparoscopic isr combined with transanal manipulation prior to the abdominal phase for two patients with t2 very low rectal cancer and total colectomy for two patients with ulcerative colitis complicated by t1 colorectal cancer; feasibility for t3 low rectal cancer could not be evaluated due to the small number of patients. |
| PubMedID- 25823771 | It has been more than 40 years since the colonoscopic surveillance program for colorectal cancer (crc) in patients with long-standing ulcerative colitis (uc) was introduced (1). |
| PubMedID- 26357617 | Risk factors for developing cca in psc patients include elevated serum bilirubin, chronic ulcerative colitis with colorectal cancer or dysplasia, variceal bleeding, proctocolectomy, and polymorphisms of the natural killer group 2, member d (nkg2d) gene (encoding a protein involved in nk cell activity).78, 82, 83 the duration of psc may not be a risk factor for the development of cca, which is contrary to the risk factors of neoplasia in inflammatory bowel disease.77 it is suggested that dominant strictures, defined as a common bile duct stenosis with less than 1.5 mm diameter remaining in the common bile duct or a common hepatic duct stenosis close to the bifurcation leaving less than 1.0 mm diameter of the common hepatic duct,84, 85 may serve as primary indicators of concomitant cca.86 it is very challenging to distinguish between benign strictures from psc activity and cca as they can have similar characteristics on imaging. |
| PubMedID- 25888857 | Avoiding restorative proctocolectomy for colorectal cancer in patients with ulcerative colitis based on preoperative diagnosis involving p53 immunostaining: report of a case. |
| PubMedID- 25797989 | Surveillance colonoscopy (sc) is considered important for the early detection and treatment of colorectal cancer (crc) in patients with ulcerative colitis (uc). |
| PubMedID- 21722342 | Sulfasalazine has even been postulated as chemo-prevention of colorectal cancer in patients with colitis ulcerosa [8]. |
| PubMedID- 21793125 | Background: ulcerative colitis (uc) is associated with colorectal cancer. |
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