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PedAM

Pediatric Disease Annotations & Medicines




Disease colitis
Phenotype C0007102|colon cancer
Sentences 14
PubMedID- 22323126 Considering the increased colon cancer risk associated with chronic colitis, we have therefore examined the effects of long-acting hgly(2)glp-2, as well as of endogenous glp-2 using the antagonist hglp-2(3-33) in two novel models of inflammation-associated colon cancer: rats fed the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (phip) and a high-fat diet (hfd) for one or three cycles, and mice with chronic dextran sodium-sulfate (dss)-induced colitis administered aom.
PubMedID- 22899889 Recently we have shown that hag reduces colon cancer associated with colitis in mice [28].
PubMedID- 20085438 Objectives: to determine the incidences of dysplasia, adenomatous polyp and colon cancer in patients with ulcerative colitis (uc) and to evaluate the risk factors.
PubMedID- 25443414 The present study explores the role of ulcerative colitis in colon cancer by investigating the activities of tyrosine kinase activated mapk pathway and various components of the pi3k pathway including pi3k, pten, pdk1, gsk3beta, akt, mtor, wnt and beta-catenin.
PubMedID- 25535472 Using the extract of ag, cui et al [39] showed that the extract suppressed colon cancer associated with colitis in the aom/dss model.
PubMedID- 23408349 Chronic intestinal inflammation predisposes to colon cancer development, but effects of female hormones on colitis-associated cancer development have not been examined.
PubMedID- 22115311 Sirt1 is also expressed in the gut where it exerts anti-inflammatory effects in acute intestinal inflammation and suppresses intestinal tumorigenesis and colon cancer associated with colitis [122-124].
PubMedID- 23202913 It has been shown that dna methylation is more frequent and more common in non-neoplastic cells in the mucosa from ulcerative colitis patients with colon cancer as opposed to those with non-neoplastic mucosa from ulcerative colitis without cancer.
PubMedID- 26507305 (45) for an overview of the older literature), but solutions were sometimes reinvented by shrewd clinical investigators who faced the problem in studies on the prognosis of transient ischemic attacks (18), of colon cancer risk in patients with colitis (16), and of multiple sclerosis (17).
PubMedID- 23095257 Although rna-sequencing data in patients affected by ibd would provide more consistency to the description of this process, the analysis performed shows a higher correlation of ulcerative colitis genomic patterns with colon cancer in comparison to crohn's disease.
PubMedID- 26296091 For example, inflammatory bowel diseases, such as ulcerative colitis, are associated with colon cancer [26].
PubMedID- 23553422 Of the 8 patients in the emergency surgery group who died during the early postoperative period, the cause of death was pneumonia in 4, intra-abdominal sepsis in 3, and perforation of the colitis associated with transverse colon cancer in 1. respiratory complications and sepsis derived from methicillin-resistant staphylococcus aureus (mrsa) or fungal infection were frequent causes of death.
PubMedID- 26189522 Here we report a case of advanced gastric cancer seen after total proctocolectomy for an early colon cancer associated with ulcerative colitis (uc).
PubMedID- 22848611 A novel murine model of inflammatory bowel disease and inflammation-associated colon cancer with ulcerative colitis-like features.

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