PedAM
Pediatric Disease Annotations & Medicines
| Disease | chronic pain |
| Phenotype | C1956089|osteophyte |
| Sentences | 1 |
| PubMedID- 24998926 | Oa is classically defined as a progressive degenerative rather than an inflammatory disease, and it is characterized by deterioration of joints, including loss of articular cartilage and subchondral bone, as well as osteophyte formation which lead to chronic pain and functional restrictions in the affected joints (figure 4).28-31 different factors can be involved in the development of oa: mostly traumatic events are causative, but there are other factors like genetic predisposition, defective position of joints, ageing and malnutrition, which all lead to similar alterations in the joint cartilage. |
Page: 1