PedAM
Pediatric Disease Annotations & Medicines
| Disease | chronic pain |
| Phenotype | C0149931|migraine |
| Sentences | 2 |
| PubMedID- 24083117 | Exclusion criteria were: other headaches but migraine, other forms of chronic pain, overuse of pain/migraine medication, psychiatric diseases, neurological diseases and other chronic diseases, intake of cns-active medications the last 3 months before the selection, intake of prophylactic medication for migraine the last 3 months before the selection, intake of other regular medications, pregnancy or risk of pregnancy and inability/unwillingness to cooperate. |
| PubMedID- 26290446 | Since the insula processes and relays afferent inputs from brain areas involved in these functions to areas involved in higher cortical function such as frontal, temporal, and parietal regions, it may be implicated as a brain region that translates the signals of altered internal milieu in migraine, along with other chronic pain conditions, through the insula into complex behaviors. |
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