PedAM
Pediatric Disease Annotations & Medicines
| Disease | chronic pain |
| Phenotype | C0019348|herpes simplex |
| Sentences | 2 |
| PubMedID- 25523148 | Background: patients with widespread unilateral chronic pain associated with recurrent herpes simplex virus (hsv) infections show functional and/or structural changes in the insula, anterior cingulate cortex, frontal and prefrontal cortices, as well as the thalamus, suggesting central dysfunction of the pain system in these patients. |
| PubMedID- 25887644 | Experimentally induced pain impacts neuronal properties and organisation in s1 and m1 [153,166] and subjects with chronic pain associated with unilateral herpes simplex virus have a decreased representation between digits 1–5 in the contralateral s1 [167]. |
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