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PedAM

Pediatric Disease Annotations & Medicines




Disease chronic pain
Phenotype C0016053|fibromyalgia
Sentences 16
PubMedID- 20506181 Intrinsic brain connectivity in fibromyalgia is associated with chronic pain intensity.
PubMedID- 20921842 Randomized trials have documented significant analgesic effects for managing chronic pain associated with fibromyalgia and diabetic peripheral neuropathic pain.
PubMedID- 21386950 In conclusion, duloxetine, a selective inhibitor for the serotonin and norepinephrine transporters, is efficacious in the treatment of chronic pain associated with fibromyalgia or diabetic neuropathy, and has a predictable tolerability profile, with adverse events generally being mild to moderate.
PubMedID- 21918649 More recently, pilot trials of low-dose naltrexone hydrochloride (ldn), which is a pharmaceutical similar to naloxone, have recently gained increasing recognition for treating chronic pain associated with fibromyalgia, multiple sclerosis, and crohn's disease [8–10].
PubMedID- 23191939 fibromyalgia represents the tip of the iceberg of chronic pain in the general population.
PubMedID- 25139588 However, emerging evidence suggests that emotional modulation of pain (but not spinal nociception) is disrupted in fibromyalgia and disorders associated with chronic pain risk (eg, major depression, insomnia).
PubMedID- 23378746 Participants were prescribed antidepressant medications for various conditions, including major depressive disorder, social anxiety disorder, and chronic pain (ie, associated with fibromyalgia).
PubMedID- 26106555 Previous findings by our group have also shown increased dmn connectivity to the insula in chronic pain patients diagnosed with fibromyalgia (napadow et al., 2010): greater insula to dmn connectivity was associated with more clinical pain.
PubMedID- 24035635 Objectives: the objectives were to compare the personality of fibromyalgia (fm) patients with other chronic painful and nonpainful disorders considering the confusion due to psychopathology and to assess the clustering of fm patients according to their personality profile.
PubMedID- 21349445 Central sensitivity syndromes: mounting pathophysiologic evidence to link fibromyalgia with other common chronic pain disorders.
PubMedID- 26186545 Similarly, our research group has recently shown that chronic pain patients with fibromyalgia syndrome manifest augmented p300 responses to both pain and non-pain pictures, suggesting increased salience and attention for somatic stimuli with even a low risk of pain [71].
PubMedID- 21953000 Collectively, studies have revealed the therapeutic potential of exercise in juvenile idiopathic arthritis, juvenile systemic lupus erythematosus, juvenile dermatomyositis, juvenile fibromyalgia and other causes of chronic pain.
PubMedID- 25304055 Objectives: fibromyalgia (fm) is one of the most common chronic pain syndromes.
PubMedID- 22842297 The role of illness perception and emotions on quality of life in fibromyalgia compared with other chronic pain conditions.
PubMedID- 23603031 Our findings demonstrate that 5-ht(2c) receptors play a critical role in muscular hyperalgesia in rim rats and suggest that 5-ht(2c) receptor agonists have therapeutic potential for treating chronic pain in patients with fibromyalgia although clinical extrapolation remains to be a future challenge.
PubMedID- 25884917 Thus, our results may provide a neurological explanation for the clinical observation that microcone treatment is helpful in chronic pain relief in patients with fibromyalgia (personal communication with katsutaro nagata), accompanying with autonomic dysfunctions.

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