PedAM
Pediatric Disease Annotations & Medicines
| Disease | chronic pain |
| Phenotype | C0003467|anxiety |
| Sentences | 29 |
| PubMedID- 20370845 | Persistent chronic pain is associated with depression and anxiety, interference with work and personal relationships and loss of independence (2). |
| PubMedID- 25983704 | Over the past 30 years, health psychologists have discovered that not just the intensity of pain, but the fear of pain is associated with functional disability, physical inactivity, and feelings of anxiety and depression in patients with chronic pain disorder (mccracken et al., 1992; vlaeyen et al., 1995; asmundson et al., 1999; crombez et al., 1999; zale et al., 2013). |
| PubMedID- 22807630 | chronic pain is associated with symptoms of anxiety and depression,5 and can have a serious adverse impact on quality of life. |
| PubMedID- 23738197 | A previous pilot indicated relationships between pain and stress, depression, and anxiety in patients with chronic pain [9]. |
| PubMedID- 23688830 | The present study evaluated the efficacy of a clinician-guided internet-delivered cognitive behaviour therapy (icbt) program, the pain course, to reduce disability, anxiety, and depression associated with chronic pain. |
| PubMedID- 24992348 | Background: chronic pain is associated with increased anxiety, depression, and maladaptive behaviors, especially in adolescents. |
| PubMedID- 25556835 | chronic pain can lead to anxiety and anxiety can enhance the sensation of pain. |
| PubMedID- 25484528 | Current fear-anxiety-avoidance models of chronic pain emphasize pain-related anxiety as a key diathesis for the development and maintenance of chronic pain. |
| PubMedID- 23805183 | Common symptoms (such as pain intensity, depression, and anxiety) in patients with chronic pain showed great variability across subjects and 60% of the cohort had normal values with respect to depressive and anxiety symptoms. |
| PubMedID- 20361062 | Aim: to investigate post-traumatic stress, pain intensity, depression, and anxiety in patients with injury-related chronic pain before and after participating in multimodal pain rehabilitation. |
| PubMedID- 26168878 | chronic pain intensity was associated with anxiety, anxiety sensitivity, and pain catastrophizing. |
| PubMedID- 24574082 | Objectives: our objective was to evaluate whether internet-delivered psychological therapies improve pain symptoms, reduce disability, and improve depression and anxiety for adults with chronic pain. |
| PubMedID- 23318753 | chronic pain is always associated with anxiety and some degree of depression. |
| PubMedID- 23835161 | Pain, on the other hand, triggers avoidance behavior, and chronic pain can even lead to depression and anxiety [2]. |
| PubMedID- 23272051 | Moreover, they suggest the possibility that a novel heteromer-directed therapeutic strategy for enhancing dor activity, could potentially be employed to reduce anxiety associated with chronic pain. |
| PubMedID- 25301891 | The study also revealed greater prevalence of anxiety and depression in patients with chronic pain (p < .05). |
| PubMedID- 24645677 | We observed not only evidence of increased central sensitization in chronic pain associated with anxiety but also a negative impact of trait-anxiety on the endogenous modulatory system in patients with long-term pain associated with higher levels of disability. |
| PubMedID- 26122003 | Of note, altered amygdala opioidergic function [41, 47, 48] has been identified to play significant roles in modification of reward and anxiety states associated with chronic pain. |
| PubMedID- 23602194 | However, acute and chronic pain are often associated with fear or anxiety [2–5]. |
| PubMedID- 25138978 | The purpose of this psychometric study was to determine the reliability and validity of the four-item patient reported outcomes measurement information system (promis) depression and anxiety scales in patients with chronic pain. |
| PubMedID- 23415758 | However, little is known about the role of tnf-alpha in the development of anxiety in animals with chronic pain. |
| PubMedID- 25337324 | chronic pain is often associated with anxiety and depression (bair, robinson, katon, & kroenke, 2003), resulting in a low health-related quality of life (otto, bach, jensen, & sindrup, 2007; gustorff et al., 2008; pagano, matsutani, ferreira, marques, & pereira, 2004; dworkin & caligor, 1988; lautenbacher & krieg, 1994). |
| PubMedID- 23597049 | Since the pfc has also been implicated in depression and anxiety [11], common co-morbidities of chronic pain, transcriptional changes in brain regions such as the pfc can also provide an explanation for these co-morbidities. |
| PubMedID- 24139217 | There was an increased risk of chronic pain among adolescents with mood or anxiety disorders versus those with hyperkinetic disorders, yet this was not present after adjusting for sex. |
| PubMedID- 24579028 | chronic pain conditions coexist with increased anxiety, perceived stress, and a higher profile of global distress when compared to asymptomatic controls. |
| PubMedID- 25277376 | Background: despite high prevalence of anxiety accompanying with chronic pain, the mechanisms underlying pain-related anxiety are largely unknown. |
| PubMedID- 21668746 | Interestingly, chronic pain is often associated with depression and anxiety, and they seem to reinforce each other [29,30]. |
| PubMedID- 25902153 | Finally, we conducted a series of exploratory analyses to test whether individual facets of neuroticism (e.g., hostility, self-consciousness, impulsivity) may be differentially-related to indices of catastrophizing and pain-related anxiety among persons with chronic pain. |
| PubMedID- 22412082 | This study aimed to examine the possible cross-sectional mediating role of sleep in the relationship of gratitude with depression and anxiety in patients with chronic pain. |
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