PedAM
Pediatric Disease Annotations & Medicines
| Disease | cholestasis |
| Phenotype | C0024523|malabsorption |
| Sentences | 3 |
| PubMedID- 23593929 | Complications of hepatic involvement can include ascending cholangitis, cholestasis with malabsorption of fat-soluble vitamins, and rarely benign or malignant liver tumors. |
| PubMedID- 24336431 | Further, cholestasis may lead to malabsorption of fat soluble vitamins (k, d, e, a), and the overall abnormal proliferation of biliary cells has reportedly led to benign or malignant tumors in older patients. |
| PubMedID- 26554665 | Although osteomalcia is rarely observed in patients with pbc [4], malabsorption as a consequence of severe cholestasis and impaired ability to convert vitamin d to 25-hydroxivitamin d can cause osteomalacia in patients with advanced pbc [10, 11]. |
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