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PedAM

Pediatric Disease Annotations & Medicines




Disease chagas disease
Phenotype C0878544|cardiomyopathy
Sentences 6
PubMedID- 24282718 In its chronic stage, chagas disease can lead to a severe cardiomyopathy for which there is currently no cure.
PubMedID- 25993486 Background: chagas disease is a cause of dilated cardiomyopathy, and information about left atrial (la) function in this disease still lacks.
PubMedID- 23089149 The treatments tested in complication trials generally did not target the infectious agent but aimed to modify the pathophysiology of the complication—for example, use of angiotensin converting enzyme (ace) inhibitors for cardiomyopathy associated with chagas disease.
PubMedID- 21408088 The same group compared 166 chronic chagas disease patients with cardiomyopathy to 80 asymptomatic patients, but observed no significant association with tnf polymorphisms [22].
PubMedID- 23451183 Elevated serum levels of macrophage migration inhibitory factor are associated with progressive chronic cardiomyopathy in patients with chagas disease.
PubMedID- 24472559 Chronic t. cruzi infection, resulting in chronic chagas disease can lead to cardiomyopathy due to the immune response damaging the tissues of the heart.

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