PedAM
Pediatric Disease Annotations & Medicines
| Disease | caroli disease |
| Phenotype | C0023895|liver disease |
| Sentences | 1 |
| PubMedID- 22007315 | Human and experimental data have suggested several potential mechanisms that could lead to cyst formation in fibropolycystic liver diseases including those of caroli's disease patients: (i) increased cell proliferation and apoptosis; (ii) enhanced fluid secretion; (iii) abnormal cell-matrix interactions; (iv) alterations in cell polarity; and (v) abnormal ciliary structure or function [7]. |
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