PedAM
Pediatric Disease Annotations & Medicines
| Disease | cardiomyopathy |
| Phenotype | C0041234|chagas\' disease |
| Sentences | 4 |
| PubMedID- 22807679 | Nonetheless, the development of severe cardiomyopathy in chagas' disease is also thought to be due to a th1-specific immune response [12]. |
| PubMedID- 21734249 | The transfer of the parasite mitochondrial kinetoplast dna (kdna) minicircle to the genome of chagasic patients can explain the pathogenesis of the disease; in cases of chagas' disease with evident cardiomyopathy, the kdna minicircles integrate mainly into retrotransposons at several chromosomes, but the minicircles are also detected in coding regions of genes that regulate cell growth, differentiation, and immune responses. |
| PubMedID- 22545173 | As we suspected, cd4+cd25+ t cells from chagas' disease patients with severe cardiomyopathy presented reduced capacity to suppress t cell proliferation when compared to free/mild cardiomyopathy patients and healthy individuals. |
| PubMedID- 23357302 | chagas' disease (cd) often leads to dilated cardiomyopathy (dcm), and during its chronic stage hematopoietic stem or progenitor cells are involved in its pathological process. |
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