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PedAM

Pediatric Disease Annotations & Medicines




Disease cardiomyopathy
Phenotype C0004153|atherosclerosis
Sentences 2
PubMedID- 20434371 Given that characteristics of dilated cardiomyopathy closely associate with atherosclerosis and are mediated by an imbalance between matrix metalloproteinases (mmps) and timps, we hypothesized that parp-1 gene deletion may protect against hf-induced cardiac hypertrophy and dilatations by altering mp-2/mmps balance in favor of a maintenance of tissue homeostasis.
PubMedID- 23050066 3, 7, and 10) had associated risk factors of atherosclerosis with ischemic cardiomyopathy, hypertension, and peripheral arterial disease.

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