PedAM
Pediatric Disease Annotations & Medicines
| Disease | c syndrome |
| Phenotype | C0030312|bone marrow failure |
| Sentences | 5 |
| PubMedID- 25741600 | Tumorigenesis initiated by repeated cell attrition and repopulation, as confirmed in different genetic models, has parallels in human cancers, exemplified in therapy-induced secondary malignancies and myelodysplastic syndromes in patients with congenital bone marrow failure syndromes. |
| PubMedID- 24765528 | Fa is a group of genetic syndromes associated with bone marrow failure, congenital abnormalities, hypersensitivity to dna-damaging agents, and a high cancer risk [1-5]. |
| PubMedID- 25332625 | Fanconi's anemia is primarily an autosomal recessive genetic disorder characterized by congenital abnormalities, defective haematopoiesis leading to bone marrow failure and increased risk of development of myelodysplastic syndrome, acute myeloid leukemia and solid tumours. |
| PubMedID- 24800039 | It has been shown to be effective in patients with bone marrow failure due to myelodysplastic syndromes (mds), graft failure, chemotherapy, or aplastic anemia. |
| PubMedID- 24032679 | The pathogenesis of bone marrow failure in myelodysplastic syndromes (mds) is an unresolved mystery. |
Page: 1