PedAM
Pediatric Disease Annotations & Medicines
| Disease | c syndrome |
| Phenotype | C0028754|adiposity |
| Sentences | 31 |
| PubMedID- 22240726 | These studies indicate that the l3 or l2 region correlate as well or better than the l4–l5 region with total visceral adiposity and markers of metabolic syndrome. |
| PubMedID- 21682752 | A similar interaction was observed between risky drinking and abdominal adiposity, a major component of the metabolic syndrome. |
| PubMedID- 21253360 | However, metabolic syndrome is associated with increased visceral adiposity and increased production of pathologic adiopokines,25) and the use of atorvastatin and fenofibric acids is associated with decreased adipokine release from visceral adipose tissue.6) the use of statin might decrease the production of pathologic adipokines in the epicardial adipose tissue, and the reduced adiopokine production might subsequently be associated with a decrease in eft. |
| PubMedID- 22923652 | However, in our much longer chronic obesity experiments, it is clear that pla2g2a is unique among spla2 isoforms examined in being dramatically overexpressed in hchf-fed rats compared with cs-fed rats, and importantly, the pla2g2a-selective inhibitor attenuated adiposity and most symptoms of metabolic syndrome in these rats. |
| PubMedID- 23091640 | Demonstrated that a hfd led to changes in the gut microbiota as well as the expected increase in adiposity and other symptoms of metabolic syndrome. |
| PubMedID- 25119754 | Objective: to evaluate the correlation between neck circumference and insulin resistance and components of metabolic syndrome in adolescents with different adiposity levels and pubertal stages, as well as to determine the usefulness of neck circumference to predict insulin resistance in adolescents. |
| PubMedID- 21150013 | Individual variations in metabolic response to the dietary constituents: indian children are predisposed to develop hyperinsulinaemia, the basic endocrine abnormality of metabolic syndrome, because of sarcopenic adiposity noted from intrauterine life6162. |
| PubMedID- 25771885 | Prospective studies have shown that both adiposity and the presence of the metabolic syndrome are predictive of future low t levels and could accelerate the age-related decline of t [12, 13]. |
| PubMedID- 23410045 | Pre-pregnancy adiposity and features of the metabolic syndrome among these young aboriginal and torres strait islander women track strongly to increased risk of hypertension in pregnancy with associated risks to the health of babies. |
| PubMedID- 22479501 | Strikingly, these rodents have developed a phenotype similar to the metabolic syndrome, with increased central adiposity, impaired glucose tolerance, hypertriglyceridemia but normal circulating corticosterone levels [19], [20]. |
| PubMedID- 23849139 | Unexplained aminotransferase elevation has been strongly associated with adiposity and other features of the metabolic syndrome [23]. |
| PubMedID- 24278117 | Recent systematic reviews have reported that sedentary behavior is associated with reduced cardiorespiratory fitness, increased adiposity and elevated risk of metabolic syndrome in the pediatric age group [3], [4]. |
| PubMedID- 24728198 | Glucocorticoids are considered the main mediators of the poor long-term outcome of an adverse intrauterine environment, by stimulating hepatic gluconeogenesis, inhibiting insulin actions on skeletal muscle and potentiating insulin's actions on visceral adipose tissue, ultimately promoting visceral adiposity and sarcopenia leading to metabolic syndrome [15]. |
| PubMedID- 24520329 | The aromatase knockout (arko) mice have been shown to harbor factors of metabolic syndrome with central adiposity, hyperinsulinemia and male-specific hepatic steatosis. |
| PubMedID- 21296145 | Emerging laboratory and epidemiological data suggest that crp is an important plausible factor for insulin resistance, adiposity and other features of the metabolic syndrome (devaraj et al., 2009). |
| PubMedID- 22347441 | *no adjustment for bmi, as central adiposity is a component of metabolic syndrome. |
| PubMedID- 23251703 | Subsequently, total fat percentage as measured by dxa scan was used as a surrogate marker for the adiposity component of metabolic syndrome. |
| PubMedID- 23824655 | In the present population-based investigation, we confirm earlier findings that fto-mediated adiposity increases the risk of metabolic syndrome and of increased crp, fasting insulin, and triglyceride levels; increased systolic and diastolic blood pressure; and decreased concentrations of hdl-c [14],[15],[17]–[19]. |
| PubMedID- 26305565 | Adipose tissue is known to be associated with metabolic syndrome including adiposity and hyperlipidemia, which can cause inflammatory changes and then lead to an increase in oxidative stress. |
| PubMedID- 23719226 | Changes in both global diet quality and physical activity level synergistically reduce visceral adiposity in men with features of metabolic syndrome. |
| PubMedID- 21775485 | Increased glomerular filtration rate in early metabolic syndrome is associated with renal adiposity and microvascular proliferation. |
| PubMedID- 21603270 | Several single-nucleotide polymorphisms (snps) in human il15 and il15ra have been described which correlate with adiposity and markers of the metabolic syndrome [10–12]. |
| PubMedID- 26092037 | Given the limited success reversing the obesity epidemic and related morbidities by focusing solely on nutrition, exercise or drug therapies, there is a compelling need to consider other potential environmental factors that could be major contributors to visceral adiposity and other aspects of metabolic syndrome that are increasing at a dramatic rate worldwide. |
| PubMedID- 21178079 | Future longitudinal studies investigating the interrelationship among 25(oh)d, adiposity, and the risk of developing metabolic syndrome and type 2 diabetes are warranted. |
| PubMedID- 22363740 | Mcp-1 has been shown to be secreted by adipose tissue in positive correlation with adiposity and features of the metabolic syndrome in humans and mice [51]. |
| PubMedID- 25285285 | Correlation of abdominal adiposity with components of metabolic syndrome, anthropometric parameters and insulin resistance, in obese and non obese, diabetics and non diabetics: a cross sectional observational study. |
| PubMedID- 25841249 | Visceral adiposity is part of the metabolic syndrome, together with insulin resistance, dyslipidemia, hypertension and inflammation. |
| PubMedID- 25755863 | Epicardial adiposity in children with obesity and metabolic syndrome. |
| PubMedID- 25097001 | We evaluated the association between the epa:ala ratio and bmi to examine whether the positive association between epa and dpa in adipose tissue and metabolic syndrome could be attributed to increased adiposity, rather than dietary intake. |
| PubMedID- 22505891 | Several studies indicate a decrease in central adiposity in men with metabolic syndrome and/or t2dm with testosterone treatment [103, 104, 107]. |
| PubMedID- PMC4428886 | Lower vitamin d is linked to increased adiposity and higher risk of metabolic syndrome. |
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