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PedAM

Pediatric Disease Annotations & Medicines




Disease c syndrome
Phenotype C0020456|hyperglycaemia
Sentences 8
PubMedID- 22913986 For example, clock/clock mutant mice become obese and develop metabolic syndrome with hepatic steatosis, hyperglycaemia, hypertriglyceridaemia, hypercholesterolaemia and hyperleptinaemia (turek et al., 2005).
PubMedID- 23942780 Common risk factors for t2dm include physical inactivity, smoking, alcohol abuse and environmental toxins, such as bisphenol a. in addition, hypertension, obesity and hyperglycaemia, 3 major hallmarks of metabolic syndrome, have been associated with increased plasma levels of angiotensin(ang) ii, a central component of the renin-angiotensin system (ras) (7–9).
PubMedID- 25861250 The agonists of ppars are therapeutically used to treat dyslipidemia and hyperglycaemia associated with the metabolic syndrome.
PubMedID- 25083916 Agonists of the nuclear receptor ppargamma are therapeutically used to combat hyperglycaemia associated with the metabolic syndrome and type 2 diabetes.
PubMedID- 23852298 These are all genetic models of metabolic syndrome and usually associated with severe hyperglycaemia and β cell exhaustion.
PubMedID- 25665169 On the contrary, icr mice fed a high-fat diet displayed symptoms of metabolic syndrome with hyperglycaemia, hyperlipidaemia and obesity.
PubMedID- 21890532 Aims: methylglyoxal (mg) overproduction has been reported in metabolic syndrome with hyperglycaemia (diabetes) or without hyperglycaemia (hypertension), and the underlying mechanism was investigated.
PubMedID- 23476686 As with our previous study, feeding a high-fat diet to sd rats led to visceral obesity associated with hyperlipidaemia, hyperinsulinaemia, and slight hyperglycaemia, which are characteristics of metabolic syndrome [11].

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