PedAM
Pediatric Disease Annotations & Medicines
| Disease | breast cancer |
| Phenotype | C1333990|lynch syndrome |
| Sentences | 4 |
| PubMedID- 23164213 | No consensus exists regarding the association of breast cancer with lynch syndrome. |
| PubMedID- 23510156 | Using the pubmed, we identified all relevant studies of breast cancer associated with lynch syndrome that were published by 15 december 2012. in the review, we included: (i) molecular studies that reported microsatellite instability and/or immunohistochemistry in breast cancer tumors of mmr gene mutation carriers; and (ii) risk studies that investigated risk of breast cancer for confirmed mmr gene mutation carriers or families or clinically and/or pathologically defined lynch syndrome families. |
| PubMedID- 22913763 | A recent study by lotsari and colleagues analyzes molecular features of breast cancers from families with lynch syndrome, including germline mutation carriers and their non-mutation carrier siblings, and controls with sporadic breast cancer. |
| PubMedID- 23294250 | We present two cases of loss of mismatch protein expression in breast cancer cases in patients with lynch syndrome and discuss the literature surrounding the subject. |
Page: 1