PedAM
Pediatric Disease Annotations & Medicines
| Disease | breast cancer |
| Phenotype | C0279130|cns metastases |
| Sentences | 13 |
| PubMedID- 24298071 | cns metastases in breast cancer: old challenge, new frontiers. |
| PubMedID- 20542996 | In summary, preclinical and clinical studies have yielded promising results regarding the role that lapatinib may have in preventing and managing cns metastases in patients with erbb2+ breast cancer. |
| PubMedID- 21253507 | Historically, the incidence of clinically appearing cns metastases in patients with breast cancer is 10–20%. |
| PubMedID- 21871802 | Herein, we retrospectively analyzed clinicopathologic data of 259 breast cancer patients with cns metastases to evaluate the association between breast cancer subtypes and cns metastasis. |
| PubMedID- 23718256 | The breast specific graded prognostic assessment (bs-gpa) showed patients with cns metastases due to breast cancer to have a median survival of 13.8 months, with the most favorable group having a median survival of 25.3 months [5]. |
| PubMedID- 25433950 | cns metastases in breast cancer patients: prognostic implications of tumor subtype. |
| PubMedID- 23740934 | cns metastases among women with breast cancer tend to occur among those who are younger, have larger tumors, and have a more aggressive histological subtype such as the triple negative and her2-positive subtypes. |
| PubMedID- 20200040 | Contrary to trastuzumab, lapatinib has activity against cns metastases in patients with her-2+ breast cancer [85–87]. |
| PubMedID- 20345334 | Nevertheless, new treatment choices have emerged considering cytotoxic and biological agents for the treatment of cns metastases in patients with breast cancer. |
| PubMedID- 24191208 | Based on our single case observation, capacitabine and lapatinib combination therapy seems as the best choice for breast cancer patients with only cns metastases. |
| PubMedID- 21987585 | This report describes this detection method and demonstrates the feasibility and significance of ctc detection in a pilot study of metastatic breast cancer patients with cns metastases. |
| PubMedID- 26277099 | Methods: information on 992 breast cancer patients with cns metastases (whose primary tumour was diagnosed between 2004 and 2010) was retrieved from the netherlands cancer registry (ncr). |
| PubMedID- 23115660 | Kim et al.17) reported that in 400 patients with cns metastases of breast cancer, 318 patients (79.5%) had pbm only, 52 patients (13%) had both pbm and lmc, and 30 patients (7.5%) had lmc only. |
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