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PedAM

Pediatric Disease Annotations & Medicines




Disease breast cancer
Phenotype C0153676|lung metastases
Sentences 13
PubMedID- 23863656 [successful ventilator weaning by trastuzumab in a her2-positive breast cancer patient with multiple lung metastases].
PubMedID- 23564790 Conclusion: our study shows that elevated circulating levels of tgf-beta and cxcl1 are associated with a poor prognosis, and higher detection of ctcs and propensity of these cells to seed lung metastases in patients with breast cancer.
PubMedID- 25889825 The resection of lung metastases in patients with breast cancer has been controversial [3-7].
PubMedID- 25156580 We reviewed data from a registry of breast cancer patients with lung metastases who underwent pulmonary metastasectomy at jikei university hospital.
PubMedID- 23531446 Increased levels of urinary pge-m, a biomarker of inflammation, occur in association with obesity, aging, and lung metastases in patients with breast cancer.
PubMedID- 22705704 She suffered from advanced right breast cancer with multiple lung metastases, which was controlled by chemotherapy with trastuzumab as the key drug.
PubMedID- 23636051 Considering the importance of the proinflammatory cox-2-derived prostaglandin e2 (pge2) in inflammation and cancer, morris and colleagues found that urinary pge-m is positively associated with obesity, smoking, and lung metastases in patients with breast cancer (4).
PubMedID- 24496139 One patient had small cell lung cancer (sclc), three had non-small cell lung cancer (nsclc), and one probably had breast cancer with lung metastases.
PubMedID- 23152023 [bi-weekly nab-paclitaxel and trastuzumab therapy effective against recurrent breast cancer with multiple lung metastases in elderly patient who had previously undergone two chemotherapeutic regimens for treatment of metastatic disease-a case report].
PubMedID- 24558636 A recent study shows that elevated circulating levels of tgf-β and cxcl1 are associated with a poor prognosis, and higher detection of circulating tumor cells and propensity of these cells to seed lung metastases in patients with breast cancer [67].
PubMedID- 20504320 In aggregate, these studies support the notion that tgf-β plays an important role in both bone-and lung metastases of basal-like breast cancer, and that inhibiting tgf-β signaling results in a therapeutic effect independently of the tissue-tropism of the metastatic cells.
PubMedID- 23829944 Although we emphasize the fact that mri ‘may be’ superior to ct for imaging breast cancer with lung metastases, it is also important to note that this conclusion is valid only when lesion boundaries and accurate volumes are essential.
PubMedID- 21494783 These studies not only support the notion that tgf-β plays an important role in both bone-and lung metastases of basal-like breast cancer, but also that targeting of the tgf-β pathway holds promise as a novel therapeutic approach for metastatic basal-like breast cancer.

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