PedAM
Pediatric Disease Annotations & Medicines
| Disease | breast cancer |
| Phenotype | C0028754|obesity |
| Sentences | 117 |
| PubMedID- 20621848 | We coded the responses into exogenous (e.g., pesticides, toxicants, and phthalates) and endogenous (e.g., diet, stress, obesity) environmental causes of breast cancer. |
| PubMedID- 26059936 | These controversies are reviewed and the complex biologic nature of the association of obesity with breast cancer addressed. |
| PubMedID- 22279254 | Hence, we conducted a hospital-based case-control study to identify the association of overweight and obesity with breast cancer. |
| PubMedID- 20196787 | obesity is associated with higher-grade breast cancers, especially in black women [19]. |
| PubMedID- 26357645 | obesity increases the risk of breast cancer in postmenopausal women through a hormonal mechanism involving the metabolism of an androgenic precursor converted to estrogen in adipose tissue.67 while the obesity is a risk factor for increasing breast cancer, it seems to be a contradiction of breast density as being reverse correlated with bmi. |
| PubMedID- 19929892 | obesity increases the risk of postmenopausal breast cancer and is associated with more advanced stage at presentation but no impact on survival. |
| PubMedID- 23714455 | In this article, the authors review the evidence linking obesity with breast cancer risk and outcomes and provide an overview of lifestyle intervention studies in patients with breast cancer. |
| PubMedID- 24833917 | Although there is no conclusive evidence to suggest the protective role of specific dietary components, alcohol consumption and obesity are associated with an increased breast cancer risk; thus lifestyle changes can lead to a lower risk of developing breast cancer. |
| PubMedID- 24913241 | The model analyzes the emergence of comorbidities (stroke, coronary obstructive disease, diabetes, and breast cancer) associated with obesity during a lifetime horizon. |
| PubMedID- 26303657 | obesity has been associated with breast cancer recurrence and poorer survival. |
| PubMedID- 24842266 | The aim of this study was to evaluate the influence of overweight and obesity in os in patients with locally advanced breast cancer (labc) treated with neoadjuvant chemotherapy. |
| PubMedID- 26424778 | Background: overweight and obesity are associated with breast cancer mortality. |
| PubMedID- 24455578 | Recent data also suggests an association of obesity with pre-menopausal breast cancer risk. |
| PubMedID- 20351736 | Conclusion: obesity at the time of diagnosis of breast cancer is associated with more advanced stages and poorly differentiated grade of cancers. |
| PubMedID- 23564622 | obesity is associated with breast cancer in post-menopausal women, and breast density is a marker of breast cancer risk. |
| PubMedID- 20711654 | On the contrary, nulliparity and obesity decrease the risk of early-onset breast cancers while are associated with higher incidence in older women. |
| PubMedID- 24214584 | Leptin is emerging as a key candidate molecule linking obesity with breast cancer. |
| PubMedID- 25880028 | Since obesity is a predictor of breast cancer incidence, especially in postmenopausal women, breast cancer manifestation, and prognosis [6,41], it is important to identify barriers to mammographic screening [4]. |
| PubMedID- 20821253 | Recently, adipose tissue and its associated cytokine-like proteins, adipokines, particularly leptin and adiponectin, have been investigated as mediators for the association of obesity with breast cancer. |
| PubMedID- 21834963 | Because obesity is associated with breast cancer progression, it is important to determine whether dietary fat per se stimulates breast cancer progression in the absence of obesity. |
| PubMedID- 25468909 | obesity is associated with increased breast cancer (brca) incidence. |
| PubMedID- 23505170 | Objective: obesity is associated with poorer breast cancer outcomes and losing weight postdiagnosis may improve survival. |
| PubMedID- 20584344 | However, postmenopausal breast cancers associated with obesity exhibit a more aggressive behavior and confer decreased overall patient survival compared to those diagnosed in non-obese individuals. |
| PubMedID- 24324792 | Amplified resistin expression may indicate insulin-resistant type ii diabetes and obesity are associated with aa breast cancer. |
| PubMedID- 26526858 | Regardless of race, both luminal er + pr+ and triple-negative breast cancers are associated with obesity during the postmenopausal period [3]. |
| PubMedID- 24260287 | Moreover, while it is well-established that diabetes and obesity increase the risk of hormone-receptor positive breast cancer in postmenopausal women [20]–[22], there is now accumulating evidence that indicates an increased risk of hormone receptor negative breast cancer in women with metabolic syndrome [23] or obesity [20]. |
| PubMedID- 23212604 | Results: compared to all other racial/ethnic groups, more white females reported heavy alcohol consumption and more black females reported obesity regardless of their breast cancer status. |
| PubMedID- 22614972 | Purpose: estrogens and androgens are elevated in obesity and associated with increased postmenopausal breast cancer risk, but the effect of weight loss on these biomarkers is unknown. |
| PubMedID- 25856214 | Childhood obesity increases breast cancer death risk in women, but levels of estrogen derivatives had not been previously studied in young children. |
| PubMedID- 20540734 | obesity is associated with increased breast cancer risk in postmenopausal women [48]. |
| PubMedID- 22640376 | Given that obesity at diagnosis of breast cancer has been associated with an increased risk of recurrence and death [43,44], it is possible that the impact of lipocalin-2 level and/or combined score on dfs could only be demonstrated in the lower bmi group, with these markers being independent prognostic factors of breast cancer. |
| PubMedID- 21143857 | In general, adolescent obesity is inversely associated with breast cancer risk [41]. |
| PubMedID- 25823469 | Epidemiological studies have linked obesity with basal-like breast cancer risk and poor disease outcome, suggesting that obesity may affect the tumor phenotype by skewing the microenvironment toward support of more aggressive tumor phenotypes. |
| PubMedID- 25476497 | obesity is associated with a worse breast cancer prognosis, particularly in estrogen receptor alpha (eralpha) positive, postmenopausal patients. |
| PubMedID- 21327461 | Overweight and obesity are associated with increased postmenopausal breast cancer risk; however, it is unclear whether losing excess weight will lower risk. |
| PubMedID- 26388139 | The associations of obesity with postmenopausal breast cancer (pbc) have been previously proven in clinical studies. |
| PubMedID- 26199932 | A direct relationship has been observed between obesity and increased risk of breast cancer [3]. |
| PubMedID- 25747851 | obesity in breast cancer--what is the risk factor. |
| PubMedID- 24458825 | A positive association of obesity with breast cancer incidence and mortality is well established. |
| PubMedID- 23625540 | obesity increases the incidence of breast cancer; 5.4%-5.6% of cases expected to occur in 2025 would be attributable to obesity if current rates are maintained (table 3). |
| PubMedID- 22125453 | Several hypotheses have been proposed to explain the association of obesity with postmenopausal breast cancer. |
| PubMedID- 23104221 | obesity accounts for <10 % of breast cancer deaths across race groups. |
| PubMedID- 24161642 | Implications for nursing: tailored message education targeting breast cancer and risk associated with obesity is useful in breast cancer screening education. |
| PubMedID- 24506358 | obesity combined with breast cancer is a public health problem, given the high incidence and prevalence of both diseases. |
| PubMedID- 25252818 | Objectives: several studies suggest that overall and central-obesity are associated with increased breast cancer (bc) risk in postmenopausal-women. |
| PubMedID- 20604969 | obesity is also associated with breast cancer risk; estrogen synthesis in adipose tissue is proposed to account for this increase in risk. |
| PubMedID- 25364153 | Association of overweight and obesity with breast cancer in india: scope for improvement. |
| PubMedID- 23127511 | Our purpose is to provide a mechanistic overview of the hypothesized relationship between diet, physical activity, and obesity with breast cancer risk and progression. |
| PubMedID- 26251693 | Hyerinsulinemia may be an underlying factor in chronic conditions such as type 2 diabetes mellitus, obesity, and certain forms of cancer, including breast cancer. |
| PubMedID- 23615120 | Overweight, obesity and risk of premenopausal breast cancer according to ethnicity: a systematic review and dose-response meta-analysis. |