PedAM
Pediatric Disease Annotations & Medicines
| Disease | breast cancer |
| Phenotype | C0020459|hyperinsulinemia |
| Sentences | 5 |
| PubMedID- 22226054 | Finally, insulin-reducing treatment can significantly diminish the growth of intravenously inoculated metastatic cells in the lungs, suggesting that therapies to lower insulin in breast cancer patients presenting with hyperinsulinemia could be a valuable strategy to reduce mortality from breast cancer metastatic progression. |
| PubMedID- 23226214 | Notably, obesity is also a cause of insulin resistance, which is characterized by hyperinsulinemia [6] that, in patients with breast cancer, has been associated with an higher probability of distant recurrence and increased mortality [7]. |
| PubMedID- 22853725 | Longitudinal studies report a higher risk for breast cancer in women with hyperinsulinemia [81-83]. |
| PubMedID- 26560078 | Whether the effect of irisin on breast cancer can be attributed to obesity-related hyperinsulinemia and insulin resistance extends beyond the scope of this work, but is a particularly interesting field of research that is worthy of thorough investigation in future studies. |
| PubMedID- 24097198 | Impact: primary prevention of breast cancer in women with hyperinsulinemia may be possible by targeting insulin signaling pathways. |
Page: 1