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PedAM

Pediatric Disease Annotations & Medicines




Disease breast cancer
Phenotype C0007682|cns disease
Sentences 1
PubMedID- 26089701 Although clinical studies suggest that patients with cns metastases who receive trastuzumab have an increased overall survival compared with patients who do not, it is well understood that penetration of trastuzumab across the blood–brain barrier is inefficient.50 therefore, there is a growing interest in using tkis to target cns disease in patients with her2-positive breast cancer.

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