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PedAM

Pediatric Disease Annotations & Medicines




Disease brain edema
Phenotype C0151740|increased intracranial pressure
Sentences 7
PubMedID- 20942959 A major component of alf is the development of brain edema leading to increased intracranial pressure and brain herniation, ultimately resulting in death [3].
PubMedID- 21056502 Background & aims: astrocyte swelling and brain edema associated with increased intracranial pressure are major complications of acute liver failure (alf).
PubMedID- 25785578 Inflammation, excitotoxicity, and brain edema all lead to increased intracranial pressure by inducing secondary brain injury, which is associated with increased morbidity and mortality if not promptly and effectively treated [6].
PubMedID- 22191058 increased intracranial pressure due to brain edema caused by the growth of metastases in the brain parenchyma is the main reason for the headache, nausea, vomiting, and papilledema [45].
PubMedID- 22269349 Due to the non-expandable skull compartment, brain edema leads to increased intracranial pressure which in turn causes reduced perfusion and oxygenation of the tissue [1].
PubMedID- 21838886 Acute encephalopathy: the criteria for diagnosis of encephalopathy were 1) impaired consciousness, 2) signs of increased intracranial pressure due to brain edema, 3) convulsions and seizures, 4) slow activity on electroencephalography lasting more than 24 h after acute onset, and 5) no bacteria or fungi on csf culture [1,2,9].
PubMedID- 20012068 Hepatic encephalopathy can lead to mild to severe neuropsychiatric symptoms, brain edema with increased intracranial pressure associated with cerebellar tonsillar, uncal and/or central diencephalic herniation, and coma.

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