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PedAM

Pediatric Disease Annotations & Medicines




Disease brain edema
Phenotype C0022116|ischemia
Sentences 4
PubMedID- 25100404 The neurological severity score was improved and both ischemia-induced brain edema and bbb leakage were reduced in msc-treated mice.
PubMedID- 26413530 Furthermore, ischemia is a cause of brain edema surrounding the hematoma region [34, 35].
PubMedID- 24312074 Traumatic brain injury leads to progressive pathophysiological changes resulting in a reduction in cerebral blood flow and a decrease in tissue oxygen levels leading to ischemia, bbb disruption with brain edema (100).
PubMedID- 20924629 Pretreatment with tgn-020 significantly reduced brain edema associated with brain ischemia, as reflected by percentage of brain swelling volume (%bsv), 12.1 ± 6.3% in the treated group, compared to (20.8 ± 5.9%) in the control group (p < 0.05), and in the size of cortical infarction as reflected by the percentage of hemispheric lesion volume (%hlv), 20.0 ± 7.6% in the treated group, compared to 30.0 ± 9.1% in the control group (p < 0.05).

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