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PedAM

Pediatric Disease Annotations & Medicines




Disease autonomic dysfunction
Phenotype C0036341|schizophrenia
Sentences 4
PubMedID- 19366982 Recent studies revealed cardiac autonomic dysfunction in patients with acute schizophrenia, which appears to be mainly related to reduced vagal and increased sympathetic modulation.
PubMedID- 26157417 Therefore, the definite influence of profound autonomic dysfunction in patients with schizophrenia for reduced life expectancy needs to be shown in long-term prospective studies.
PubMedID- 22073161 Background: schizophrenia is associated with autonomic dysfunction and this may increase cardiovascular mortality.
PubMedID- 25287469 Methods: to examine whether acute schizophrenia is associated with cardiac autonomic dysfunction, 314 unmedicated patients with acute schizophrenia and 409 healthy volunteers, aged 18-65 years, were recruited for a case-control analysis.

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