PedAM
Pediatric Disease Annotations & Medicines
| Disease | autonomic dysfunction |
| Phenotype | C0018799|heart disease |
| Sentences | 2 |
| PubMedID- 26483614 | Parasympathetic activity certainly appears to be decreased in chronic heart failure patients, but the number of cardiac muscarinic receptors is not altered.9 in ischemic animal models, the sensory endings of both vagal and sympathetic afferent fibers are mechanoreceptors and fire with cardiac ischemia.10,11 in addition, this cardiac sympathetic afferent activity produces a tonic and reflex inhibition of cardiac vagal efferent activity, namely, the cardiocardiac sympathetic reflex.12 this mechanism can be applied to autonomic dysfunction in patients with other heart disease accompanied by cardiac dilatation and can be antagonized or limited by beta-adrenergic blockade. |
| PubMedID- 20097685 | Chronotropic incompetence and autonomic dysfunction in patients without structural heart disease. |
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