PedAM
Pediatric Disease Annotations & Medicines
| Disease | atrophic gastritis |
| Phenotype | C0002892|pernicious anemia |
| Sentences | 3 |
| PubMedID- 22876245 | Additional clinical features are less common, and include diabetes type i, hypothyroidism, atrophic gastritis with or without pernicious anemia (biermer’s disease), cutaneous manifestations (alopecia areata, vitiligo, transient skin rash during fever episodes, non-infectious nail dysplasia), ocular symptoms (keratoconjunctivitis, dry eye, iridocyclitis, cataract, retinal detachment, and optic atrophy; merenmies and tarkkanen, 2000), enamel dysplasia, hyposplenism/asplenia (implying vaccination against streptococcus pneumonia,haemophilus influenzae, and hepatitis b as well as antibiotic prophylaxis), autoimmune hepatitis, tubulo-interstitial nephritis, or organized pneumonitis. |
| PubMedID- 23314667 | Although it depends on the series, approximately 25% of apeced patients are affected by gastrointestinal (gi) manifestations, mainly autoimmune-related disorders like autoimmune hepatitis, atrophic gastritis with or without pernicious anemia (biermer disease), intestinal infections, and malabsorption. |
| PubMedID- 23432909 | A severe (>1000 pg/ml) elevation of fasting serum gastrin concentration is usually suggestive for zollinger–ellison syndrome; on top of this, the use of acid suppressant medication (both proton pump inhibitors or h2-receptor antagonists), the presence of h. pylori infection and autoimmune achlorhydric atrophic gastritis without or with pernicious anemia may lead to mild-to-moderate hypergastrinemia [4,5]. |
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