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PedAM

Pediatric Disease Annotations & Medicines




Disease astrocytoma
Phenotype C0017636|glioblastomas
Sentences 8
PubMedID- 21804458 Only secondary glioblastomas (arising from low grade astrocytoma) were positive for c-erbb-2 protein, and all of the primary (arising “de novo”) glioblastoma were negative for c-erbb-2 protein.
PubMedID- 23258846 Results: mct1, mct4, and cd147 were overexpressed in the plasma membrane of glioblastomas, compared with diffuse astrocytomas and nonneoplastic brain.
PubMedID- 24610491 In brain tumors, glur1 subunit was differentially expressed according to the tumor grading, being elevated in glioblastomas when compared with anaplastic astrocytomas and low-grade astrocytomas, hence correlating with tumor aggressiveness (de groot et al.
PubMedID- 26165699 We found that rab27b was hypomethylated in high-grade glioma (anaplastic gliomas and glioblastomas) compared with low-grade glioma (astrocytoma, oligodendrocytoma and oligoastrocytoma) (p=0.02).
PubMedID- 24039448 There was no statistically significant difference regarding perivascular cd3 infiltrate in glioblastomas compared with pilocytic astrocytomas (p = 0.235).
PubMedID- 20704656 In this study 59 paediatric pilocytic astrocytomas were compared with 62 adult glioblastomas, as a prototype of tumour angiogenesis.
PubMedID- 25602259 In the present investigation, we demonstrate for the first time that the expression of these two transcriptionally repressive hkmts is up-regulated in astrocytic tumors with glioblastomas displaying elevated cytoplasmic suv39h1 and setdb1, but intriguingly lower nuclear suv39h1.
PubMedID- 20423517 High-resolution copy number analysis of glioma samples also revealed recurrent gain of multiple sub-regions of chromosome 12 in secondary glioblastomas arising from lower grade astrocytomas [45].

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