PedAM
Pediatric Disease Annotations & Medicines
| Disease | asthma |
| Phenotype | C0042769|viral infection |
| Sentences | 20 |
| PubMedID- 25109477 | Furthermore, viral infections are associated with asthma exacerbations by mechanisms that are not fully understood. |
| PubMedID- 21569568 | Furthermore, our data indicate the absence of association of the viral infection with asthma is not restricted to non-atopic asthma, but also to atopic asthma. |
| PubMedID- 25155282 | Epidemiological observations have demonstrated that several important lifestyle and environmental factors including obesity, urban living, dietary patterns such as food low in antioxidants and fast food, non-breastfeeding, gut flora imbalance, cigarette smoking, air pollution, and viral infection are associated with asthma exacerbations in children. |
| PubMedID- 22004287 | The sputum of asthmatic patients with confirmed viral infection contains high levels of eosinophilic cationic protein [8]. |
| PubMedID- 26322310 | Children born preterm often display reduced lung function, increased re-hospitalization following a respiratory viral infection, and incidence of non-atopic asthma (20, 21). |
| PubMedID- 23242778 | Characterisation of winter respiratory viral infections in patients with asthma and copd in qatar. |
| PubMedID- 24098299 | In this regard, it is crucial to recognize and understand both the similarities and differences of clinical features in patients with copd and/or asthma associated with respiratory viral infections, especially in the exacerbative stage. |
| PubMedID- 23986756 | asthma inception is associated with respiratory viral infection, especially infection with respiratory syncytial virus (rsv) and/or human rhinovirus (hrv), in the vast majority of cases. |
| PubMedID- 23452625 | The pathogenesis of asthma is frequently associated with airway viral infection. |
| PubMedID- 25901797 | The importance of bacterial and viral infections associated with adult asthma exacerbations in clinical practice. |
| PubMedID- 22966430 | Thus, pro-inflammatory cytokines, inflammatory mediators and substances in the airway mucosa and submucosa, including il-6, il-11, icam-1, ecp, ltc4, ltd4, and histamine, may induce airway inflammation and smooth muscle contraction in asthma patients with viral infections. |
| PubMedID- 22948082 | Background: airway viral infections provoke exacerbations of asthma and chronic obstructive pulmonary disease. |
| PubMedID- 23675190 | This may explain the reduced steroid responsiveness seen in asthma patients with viral infections (54, 55). |
| PubMedID- 24133489 | (2011) mentioned above showed that 7 (31.8%) of 22 asthmatic children with a(h1n1)pdm09 viral infection admitted to a hospital between october and december 2009 were not previously diagnosed with asthma. |
| PubMedID- 23429916 | The onset, progression and exacerbations of asthma are frequently associated with viral infections of the lower respiratory tract. |
| PubMedID- 23060458 | Although rhinoviral infections, a major cause of asthma exacerbations, occur predominantly in upper airway bronchial epithelial cells, monocytic-lineage cells are implicated in establishing the inflammatory microenvironment observed during the disease. |
| PubMedID- 22540290 | Many cases of asthma start with a viral infection. |
| PubMedID- 20410486 | These cells may be particularly important in determining the nature of immune responses to viral infections in patients with allergic asthma as well those with other atopic diseases. |
| PubMedID- 23962134 | In addition to cytokine/chemokine profiles, the increased systemic concentration of those molecules could activate circulating leukocytes with further deleterious effects in the lung.1,2 therefore, the aim of this study was to describe changes in several inflammatory cytokines (il-1β, tnf-α), th2 cytokines (il-4, il-5), and chemokines as mcp-1 (monocyte chemoattractant protein-1) and rantes (regulated on the activation normal t cell expressed and secreted) in the systemic circulation during acute viral infection in patients with an asthmatic and a non-asthmatic background and their relationship with the respiratory infection type (upper and lower) and type of virus infection. |
| PubMedID- 21448631 | We conclude that not all viral infections in children with asthma lead to an asthma exacerbation and the attributing effect of different triggers of asthma exacerbations in children vary across different time periods and across different localities. |
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