PedAM
Pediatric Disease Annotations & Medicines
| Disease | aspergillosis |
| Phenotype | C0027947|neutropenia |
| Sentences | 7 |
| PubMedID- 23843366 | Background: aerosolized liposomal amphotericin b may reduce the incidence of invasive pulmonary aspergillosis in adults with chemotherapy-induced prolonged neutropenia with less nephrotoxicity. |
| PubMedID- 24744620 | The role of multidetector computed tomography in the early diagnosis of invasive pulmonary aspergillosis in patients with febrile neutropenia undergoing hematopoietic stem cell transplantation. |
| PubMedID- 23467602 | Although the high mortality rate of pulmonary invasive aspergillosis (ia) in patients with prolonged chemotherapy-induced neutropenia (pcin) can be reduced by timely diagnosis, a diagnostic test that reliably detects ia at an early stage is lacking. |
| PubMedID- 20212399 | Part i: focus on febrile neutropenia, invasive aspergillosis, combination antifungal therapy and invasive candidiasis in immunocompromised pediatric patients. |
| PubMedID- 23799048 | The choice of accelerated failure time models was guided by empirical findings suggesting that each hazard rate depends not only on observed characteristics, but also on the time elapsed in each state: (a1) the risk of invasive aspergillosis increases with neutropenia duration in patients treated with chemotherapy for acute myeloid leukemia [4], [5]; by contrast, (a2) the risk of invasive aspergillosis becomes flat or may even decrease during antifungal therapy as a result of its preventive efficacy [6]; (b1) the likelihood to start empirical antifungal therapy increases with neutropenia duration as clinicians may suspect the risk of invasive aspergillosis and other invasive fungal diseases; (b2) the likelihood to stop empirical antifungal therapy increases with treatment duration as treatment is stopped at neutropenia recovery. |
| PubMedID- 26366292 | Invasive pulmonary aspergillosis patients with neutropenia or normal white blood cell counts have the same histopathological pattern, that is, invasive fungi with an absence of host inflammation.2 this finding also characterises pulmonary mucormycosis.3 therefore, other causes may account for the absent or weak inflammatory infiltrate in these diseases. |
| PubMedID- 25956843 | Chemotherapy-induced neutropenia can be complicated by invasive pulmonary aspergillosis (ipa). |
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