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PedAM

Pediatric Disease Annotations & Medicines




Disease artery disease
Phenotype C0497327|dementia
Sentences 2
PubMedID- 21045164 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (cadasil) is a dominantly inherited small artery disease that leads to dementia and disability in mid-life.
PubMedID- 21547149 Two pathophysiological mechanisms, sharing common risk factors, lead to dementia associated with small-artery disease [11]: one possible mechanism is defined by occlusion of an arterial lumen, which conducts to a complete infarct (lacunar infarct) and leads to dementia due to the disruption of a neural pathway.

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