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PedAM

Pediatric Disease Annotations & Medicines




Disease artery disease
Phenotype C0149931|migraine
Sentences 5
PubMedID- 21631478 Antagonism of calcitonin gene-related peptide, which does not appear to cause vasoconstriction, may allow for treatment of migraine in patients with coronary artery disease.
PubMedID- 25206386 Indeed, in 2012, a randomized clinical trial found that a calcitonin gene-related peptide receptor antagonist was well tolerated in the treatment of migraine in patients with coronary artery disease[15].
PubMedID- 22406987 The new acute drug, telcagepant, a calcitonin gene-related peptide (cgrp) antagonist, is safe for long-term use (up to 18 months) in migraine patients with stable coronary artery disease in whom the use of triptans is not advisable.
PubMedID- 22221076 Conclusion: the study was underpowered due to enrollment difficulties and did not demonstrate a significant efficacy difference between telcagepant and placebo for the treatment of a migraine attack in patients with stable coronary artery disease.
PubMedID- 23602119 Recent data suggest that migraine is also associated with coronary artery disease.

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