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PedAM

Pediatric Disease Annotations & Medicines




Disease arteriosclerosis
Phenotype C0598608|hyperhomocysteinemia
Sentences 5
PubMedID- 24231341 hyperhomocysteinemia (hhcy) is associated with cardiovascular disease, atherosclerosis and reactive oxygen species generation.
PubMedID- 25744495 Severe arteriosclerosis with hyperhomocysteinemia was first reported in association with a rare genetic condition in humans, which is also characterized by abnormal cobalamine metabolism and cbs deficiency12.
PubMedID- 22836325 [inflammation of the vascular wall and hyperhomocysteinemia in patients with atherosclerosis obliterans of lower limb arteries].
PubMedID- 23697869 Several different mechanisms how hyperhomocysteinemia can lead to atherosclerosis are described, such as inflammation, oxidative stress and enhanced lipogenesis [11,12].
PubMedID- 21799811 hyperhomocysteinemia leads to precocious atherosclerosis which results in lower blood flow in testicular arteries, resulting in alteration in spermatogenesis [2].

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