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PedAM

Pediatric Disease Annotations & Medicines




Disease arteriosclerosis
Phenotype C0028754|obesity
Sentences 36
PubMedID- 26141940 The aim of this study is to evaluate the impact of fabp4 polymorphisms on fabp4 plasma levels and subclinical arteriosclerosis in patients with obesity, metabolic syndrome (ms) or type 2 diabetes (t2dm).
PubMedID- 26288662 Third, we only included korean men aged 19–80 years of age, therefore additional studies are needed to examine the associations of carotid atherosclerosis with obesity subtypes in korean women.
PubMedID- 21106050 Vague first identified android (upper-body or abdominal) obesity as being associated with diabetes and atherosclerosis over 50 years ago [13].
PubMedID- 20678219 Physical inactivity and obesity are potential mediators of accelerating arteriosclerosis and the development of chd seen among refugee women.
PubMedID- 23773229 In the < 40 y age group, male gender, nonwhite race, stable partner, hypertension, cholesterol ≥ 240 mg/dl, triglicerydes ≥ 150 mg/dl, fasting glucose ≥ 100 mg/dl, waist circumference, overweight and obesity were significantly associated with subclinical atherosclerosis after adjustment for age.
PubMedID- 25155902 Association of metabolically healthy obesity with subclinical coronary atherosclerosis in a korean population.
PubMedID- 24298454 Conclusion: sh, the earliest form of thyroid failure, has negative metabolic effects on the affected subjects.sh could be one of the causes of secondary hyperlipidaemia and should be viewed as an independent risk factor for atherosclerosis, along with obesity, hypertension, diabetes, etc.
PubMedID- 26169265 The aim of the present study was to determine whether nafld or abdominal obesity is more associated with subclinical atherosclerosis in apparently healthy korean men.
PubMedID- 24719352 Conclusions: obesity is differentially associated with subclinical coronary atherosclerosis, according to the burden of cvd risk.
PubMedID- 26328532 Background: obesity is associated with cardiac dysfunction, atherosclerosis, and increased cardiovascular risk.
PubMedID- 20847813 The development of atherosclerosis in obesity stems from a constellation of interrelated proatherogenic mechanisms.
PubMedID- 23451155 Second, obesity is associated with atherosclerosis and other atherogenic determinants, including hypertension, hyperinsulinemia and dyslipidemia.
PubMedID- 24675912 obesity is independently associated with coronary atherosclerosis in youngadults1.
PubMedID- 21190590 In our previous study of a specific atherosclerosis-prone population with obesity and metabolic syndrome (mets), we did not find any significant role for at-ldl [19].
PubMedID- 25874192 It is well known that obesity is associated with stroke, atherosclerosis, coronary artery disease, and endocrinal disorders.
PubMedID- 21779189 Leptin and adiponectin can be more relevant to atherosclerosis in subjects with obesity and diabetes mellitus than conventional atherosclerotic factors such as bp and lipid levels [7, 14, 15].
PubMedID- 22532774 Recent studies have demonstrated biglycan to be upregulated in a murine model of diet-induced obesity with atherosclerosis,23 to be involved in vascular and proatherogenic remodeling in a rat model of metabolic syndrome,24 to be proangiogenic,25 and interestingly, to have upregulated expression in parallel with matrix degradation genes in white adipose tissue from db/db mice fed a high fat diet.20biglycan has also been demonstrated to be upregulated in human omental compared to lean adipose tissue.26 this evidence builds upon the hypothesized role for biglycan in adipose tissue homeostasis, particularly in states of obesity where ecm remodeling is required for adipose tissue expansion.
PubMedID- 26274965 obesity fosters the development of hypertension, vascular atherosclerosis (including coronary atherosclerosis), varicose veins, and venous thrombotic events (cerebral strokes, myocardial infarction) [60].
PubMedID- 22507608 This study aimed to investigate the best anthropometric obesity indicator for diagnosis of initial stage of atherosclerosis by cimt.
PubMedID- 26394050 While the effect size was small (β = -.097), the impact of the number of vascular burden factors (hypertension, diabetes, obesity, smoking, atherosclerosis), with hypertension in particular, on hemodynamic responses within left ifj complements previous positron emission tomography findings.
PubMedID- 20158910 atherosclerosis in obesity, metabolic syndrome and t2dm is initiated by damage/activation of the endothelium [2,4,8].
PubMedID- 24843601 Adipocytokines play an important role in the pathogenesis of atherosclerosis through inflammation associated with obesity and metabolic syndrome.
PubMedID- 25648331 It was also evaluated as a marker of atherosclerosis in patients with high risk (obesity and obesity-related metabolic complications such as diabetes) without direct evidence of developing coronary artery disease (cad) [5–7].
PubMedID- 23788131 Mets comprises a cluster of cardiovascular risk factors (low hdl-c, elevated bp, fasting glucose and tg, and abdominal obesity)1 leading to accelerated atherosclerosis and an increased risk of type 2 diabetes.
PubMedID- 22430029 In the present study, we determined disparities in the relationships of obesity measures with atherosclerosis between women with ra from a developing black compared to a developed caucasian population.
PubMedID- 25650072 It has been linked extensively with obesity leading to cvds including atherosclerosis, myocardial infarction, and stroke [51, 52].
PubMedID- 22408412 These reports have demonstrated a reduction in the incidence of cvd and atherosclerosis with obesity by natural product therapy.
PubMedID- 20170522 As human obesity is associated with hyperleptinemia and atherosclerosis, it was shown that leptin, in addition to its angiogenic properties, exerts proatherogenic effect on endothelial cells by increasing reactive oxygen species (ros) formation.
PubMedID- 23967179 Further investigations should be performed to clarify whether obesity-associated increase of lps relates to atherosclerosis through endothelial adiponectin.
PubMedID- 23056109 Increased adipose tissue related to all cause mortality 11-12 it seems that association of other atherosclerosis risk factors with obesity has main ruls.
PubMedID- 24410779 These experimental and clinical studies indicate that the no-dependent vasodilatory effects of leptin become impaired, and by this mechanism, leptin may contribute to endothelial dysfunction and the progression of atherosclerosis in patients with obesity and/or mets.
PubMedID- 21910745 Inflammation and insulin resistance (ir) play critical roles in the obesity-linked development of cvd, such as atherosclerosis, hypertension and restenosis.
PubMedID- 23420493 They have been implicated in lipid digestion and obesity, activation of immune cells, asthma, atherosclerosis, acute respiratory distress syndrome and host defense against bacteria, viruses and parasites (5–8).
PubMedID- 19498343 To determine whether apoe(-/-) mice would develop obesity with accelerated atherosclerosis, we fed mice diets containing 10 (low fat (lf)) or 60 (high fat (hf)) kcal % from fat for 17 weeks.
PubMedID- 20368778 In this context, leptin may be one of the mediators responsible for the low-level systemic inflammation that may be present in metabolic syndrome-associated chronic pathologies such as atherosclerosis, which is associated with obesity, especially central obesity.
PubMedID- 22701780 Carried out a cross-sectional study to examine the association of obesity parameters with atherosclerosis in obese patients.

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