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PedAM

Pediatric Disease Annotations & Medicines




Disease arteriosclerosis
Phenotype C0020676|hypothyroidism
Sentences 6
PubMedID- 26224049 Overt hypothyroidism is associated with accelerated atherosclerosis and an increased risk of coronary artery disease (cad).1–3 while some of these effects can be explained by a higher prevalence of hypertension and dyslipidemia in patients with hypothyroidism,4–7 not all individuals with hypothyroidism have abnormal blood pressure or lipid profiles.8 in addition, studies have shown an increased risk of all-cause mortality9 and cardiovascular events10 in patients with hypothyroidism, even after adjusting for the presence of conventional cardiovascular risk factors, implicating other factors in their elevated risk.
PubMedID- 24145612 hypothyroidism is associated with atherosclerosis, dyslipidemia, diastolic hypertension, impaired endothelial dysfunction, and insulin resistance (45).
PubMedID- 22363888 Clinical hypothyroidism is associated with premature atherosclerosis and increased prevalence of coronary disease.
PubMedID- 24517143 Context: increasing evidence shows that subclinical hypothyroidism (sch) is associated with atherosclerosis (ath), but the association remains controversial.
PubMedID- 23776901 [1] although the association of atherosclerosis with overt hypothyroidism has been well established, there is still controversy about its association with subclinical hypothyroidism (sch) despite exclusive research.
PubMedID- 22147096 Objective: the aim of this study was to assess whether subclinical hypothyroidism (sch) is associated with carotid atherosclerosis, as well as dyslipidemia, and arterial hypertension.

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