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PedAM

Pediatric Disease Annotations & Medicines




Disease arteriosclerosis
Phenotype C0018799|heart disease
Sentences 50
PubMedID- 25861201 Introduction: atherosclerosis leading to ischemic heart disease (ihd) is the most common cause of cardiac deaths worldwide.
PubMedID- 21649590 Purpose: to assess effects of niacin on risk factors of atherosclerosis in men with coronary heart disease (chd) and high lipoprotein(a) [lp(a)] levels.
PubMedID- 21942962 [prevalence and clinical significance of multifocal atherosclerosis in patients with ischemic heart disease].
PubMedID- 21490772 Therefore, the addition of extended-release niacin to statin therapy slowed the progression of atherosclerosis among individuals with known coronary heart disease and moderately low hdl-cholesterol [18].
PubMedID- 23590337 Ir was also seen to be an independent predictor of atherosclerosis plaque progression in patients with coronary heart disease in both the diabetic and non-diabetic population [20].
PubMedID- 25944976 Systemic inflammation plays a major role in the development of atherosclerosis leading to coronary heart disease.
PubMedID- 23062036 In the days before atorvastatin (or ‘statins’; hmg coa reductase inhibitors) was proven to reduce low density lipoprotein (ldl) cholesterol [67] and as a result reduce the risk of coronary heart disease due to atherosclerosis [68-70], a variety of drugs that interfered with cholesterol metabolism were evaluated.
PubMedID- 22725704 Hypercholesterolemia plays a key role in the development and progression of atherosclerosis and can lead to cardiac heart disease.
PubMedID- 20526039 atherosclerosis in patients with cyanotic congenital heart disease.
PubMedID- 21633059 By the 1950s and 1960s, research had associated atherosclerosis with heart disease and established that artery-clogging plaques were composed largely of cholesterol.
PubMedID- 20503072 Pylori) strains infection on coronary atherosclerosis in patients with coronary heart disease and to elucidate how cytotoxin-associated gene a (caga)-positive h.
PubMedID- 22489713 Tac determination through a modified trap assay has been reported as a useful ex vivo biomarker for atherosclerosis staging in patients with coronary heart disease [99].
PubMedID- 24167546 It has been shown that atherosclerosis, the underlying cause of coronary heart disease, can occur even in children and adolescents [1]–[3].
PubMedID- 20965587 Reduced body iron stores and atherosclerosis in patients with cyanotic congenital heart disease.
PubMedID- 21208444 For example, pik3cg has been suggested as a heart disease target because of its roles in atherosclerosis related inflammation [13] and pathogenesis of cardiac hypertrophy and heart failure [14].
PubMedID- 23761967 It should also be noted that coronary heart disease due to atherosclerosis is increasing.
PubMedID- 23953044 Aim of the study was to assess prognostic role of high sensitivity c-reactive protein (crp) in progression of atherosclerosis in patients with ischemic heart disease (ihd) in a year after coronary artery bypass grafting (cabg).
PubMedID- 21490774 Epidemiological studies have revealed that higher levels of hdl cholesterol in blood are associated with protection and that lower levels of hdl cholesterol in blood are associated with increased risk for atherosclerosis leading to heart disease [15].
PubMedID- 26328503 Coronary heart disease because of atherosclerosis is still the most common cause of mortality.
PubMedID- 22709409 Insulin resistance is an independent predictor for atherosclerosis plaque progression in patients with coronary heart disease in both the diabetic and non-diabetic population.
PubMedID- 23536941 Aim: to study the spread of a number of indicators of subclinical atherosclerosis in patients with coronary heart disease (chd) and the pattern of their relationship to their functional state and muscle mass.
PubMedID- 26108894 In spite of these advances, cvd, specifically, ischemic heart disease due to coronary atherosclerosis is the leading cause of cardiovascular death of women in the usa.
PubMedID- 23936087 The risk of atherosclerosis, a major cause of coronary heart disease (chd) is inversely proportional to high density lipoprotein (hdl) cholesterol [1], [2].
PubMedID- 26576421 atherosclerosis, the primary cause of heart disease and stroke, is responsible for approximately 50% of all deaths in western societies and is the leading cause of deaths worldwide [1].
PubMedID- 20364398 Interleukin-4 (il-4) has important role in immune cell chemotaxis, formation of endothelial cell adhesion molecules and has numerous anti-inflammatory effects which prevent the complications of atherosclerosis, the primary cause of coronary heart disease (chd).
PubMedID- 24253420 It is widely believed that coronary heart disease begins due to atherosclerosis, and that atherosclerosis is basically inflammation.
PubMedID- 22413998 Hyperlipidemia, also known as hyperlipoproteinemia or high cholesterol, is caused by abnormal lipid and lipoprotein metabolism, which is a disorder characterized by abnormally high concentration of lipids (fats) in the blood that are correlated with the development of atherosclerosis, the underlying cause of coronary heart disease (chd) and stroke [1].
PubMedID- 23956253 Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the european atherosclerosis society.
PubMedID- 22159319 Since the use of ptca in the treatment of coronary atherosclerosis, numerous patients with coronary heart disease have benefited from pci, but the relatively high incidence of restenosis after pci has been a major problem, despite the short-term success of this technique.
PubMedID- 23119182 Because of these abnormalities, it is thought that rheumatologic disorders have been associated with premature atherosclerosis leading to ischemic heart disease at young ages.
PubMedID- 25842659 Conclusion: specific features of the cardiovascular pathology and a course of coronary heart disease in combination with atherosclerosis of the abdominal aorta and its visceral branches are revealed.
PubMedID- 22291840 A 74-year-old male with generalized atherosclerosis being the cause of ischaemic heart disease, abdominal aortic and right common iliac artery aneurysm, subacute ischaemia of the left leg with dry necrosis of the 5th toe of the left foot, and also with renal failure, arterial hypertension and permanent atrial fibrillation, was hospitalised due to acute coronary syndrome with additional troponin values.
PubMedID- 23840954 The uptake of large amounts of lipids from plasma lipoproteins via endocytosis by macrophages in the artery wall to form lipid-engorged foam cells is an important initiating event in the development of atherosclerosis, a major cause of heart disease.
PubMedID- 21334453 atherosclerosis, the primary cause of coronary heart disease, is an inflammatory disorder orchestrated by the action of cytokines.
PubMedID- 21808565 Diabetes is also an important factor in accelerating the hardening and narrowing of the arteries (atherosclerosis), leading to strokes, coronary heart disease, and other large blood vessel diseases.
PubMedID- 24748883 [12],[13] reports also indicated insulin resistance is an independent predictor of atherosclerosis plaque progression in patients with coronary heart disease,[14] and the increased plasma ffas levels were an important cause of obesity-associated insulin resistance.
PubMedID- 20857186 Patients were made aware that cac identifies underlying coronary atherosclerosis and is associated with incident heart disease.
PubMedID- 23637837 High levels of apob can lead to plaques that cause vascular disease (atherosclerosis), leading to heart disease [18].
PubMedID- 25609953 Ischemic heart disease due to coronary atherosclerosis or spasm is one of the leading causes of death and disability worldwide.
PubMedID- 23390466 The relationship between smoking and coronary heart disease, the effects of smoking on the atherosclerosis process, and the beneficial effects of smoking cessation are well known.
PubMedID- 24713330 The observation that patients were strictly controlled with statins after an ischemic heart disease or diagnosis of severe atherosclerosis to prevent ischemic heart disease induced a paradoxical result.
PubMedID- 25933642 Even though a large number of women have obstructive atherosclerosis as a cause of ischemic heart disease, a substantial number of women do not.
PubMedID- 23237394 [effect of type 2 diabetes mellitus on extent of multifocal atherosclerosis in patients with ischemic heart disease].
PubMedID- 21249329 The addition of extended-release niacin to statin therapy significantly increased hdl cholesterol and slowed the progression of carotid atherosclerosis among individuals with known coronary heart disease [8].
PubMedID- 22956783 atherosclerosis, the foremost cause of coronary heart disease, is a multifactorial andmultistep disease.
PubMedID- 20591344 Advanced atherosclerosis, through thrombosis, leads to ischemic heart disease and ischemic stroke, the leading causes of death and disability worldwide.
PubMedID- 21343206 atherosclerosis, the underlying cause of coronary heart disease and ischaemic stroke, is increasingly understood to be a chronic, low grade inflammatory disease of the arterial wall.4 increased levels of inflammatory markers have been associated with risk of cardiovascular disease.5 6 new studies have examined not only the effect of alcohol on lipid levels and haemostatic factors but also on other measures of inflammation and endothelial cell function as well as levels of adipocyte hormones.
PubMedID- 25415545 atherosclerosis, the root cause of ischemic heart disease, is promoted by risk factors like elevated plasma low-density lipoprotein, low plasma high-density lipoprotein, smoking, hypertension, and diabetes mellitus.
PubMedID- 22695460 Lipid disorders (e.g., high blood cholesterol and triglycerides) increase the risk for atherosclerosis, which can lead to coronary heart disease (chd), which accounts for a substantial proportion of cardiovascular mortality.
PubMedID- 21157110 Background: coronary artery calcification (cac) scores are widely accepted to predict risk of coronary heart diseases and are associated with atherosclerosis in other vasculatures.

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