PedAM
Pediatric Disease Annotations & Medicines
| Disease | aortic aneurysm |
| Phenotype | C0024796|marfan syndrome |
| Sentences | 12 |
| PubMedID- 26506064 | Furthermore, patients with marfan syndrome and other forms of inherited thoracic aortic aneurysm taking ccbs display increased risk of aortic dissection and need for aortic surgery, compared to patients on other antihypertensive agents. |
| PubMedID- 19879959 | We have described that the progression of thoracic aortic aneurysm in marfan syndrome is accompanied with aortic vascular dysfunction. |
| PubMedID- 23260989 | marfan syndrome with ascending aortic aneurysm: value of cardiac computed tomography. |
| PubMedID- 24527681 | Medical treatment of aortic aneurysms in marfan syndrome and other heritable conditions. |
| PubMedID- 23407346 | Giant aortic aneurysm in marfan syndrome. |
| PubMedID- 20871099 | Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe marfan syndrome. |
| PubMedID- 23496804 | Exclusion criteria were: (i) marfan syndrome or history of familial aortic aneurysm, (ii) internal ascending aortic diameter greater than 4.5 cm based on echocardiographic measurements, (iii) left ventricular ejection fraction <55%, (iv) moderate or severe aortic stenosis, (v) moderate or severe aortic regurgitation, (vi) aortic valve replacement, (vii) aortic coarctation, and (viii) blood pressure >160/90 mmhg. |
| PubMedID- 25096902 | Impact of aortic aneurysm on hospitalizations in patients with marfan syndrome: a multi-institutional study. |
| PubMedID- 21315290 | aortic aneurysm can result from both marfan syndrome (mfs) and hypertension. |
| PubMedID- 25596402 | Hybrid treatment for thoracoabdominal aortic aneurysms in patients with marfan syndrome. |
| PubMedID- 25238995 | In marfan syndrome (mfs), development of thoracic aortic aneurysms (taas) is characterized by degeneration of the medial layer of the aorta, including fragmentation and loss of elastic fibers, phenotypic changes in the smooth muscle cells, and an increase in the active form of transforming growth factor-beta (tgfbeta), which is thought to play a major role in development and progression of the aneurysm. |
| PubMedID- 21317477 | Dissecting aortic aneurysm with marfan syndrome. |
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