PedAM
Pediatric Disease Annotations & Medicines
| Disease | antiphospholipid syndrome |
| Phenotype | C0000786|miscarriage |
| Sentences | 6 |
| PubMedID- 20393166 | Antiphospholipid antibodies (apl) represent an important risk factor for thrombosis and recurrent miscarriage in patients with antiphospholipid syndrome (aps). |
| PubMedID- 24040195 | In women with recurrent miscarriage and a diagnosis of antiphospholipid syndrome (aps), treatment with aspirin and heparin has been suggested to improve the pregnancy outcome, although findings from available randomized trials have been inconsistent [11], [12], [13]. |
| PubMedID- 20378110 | Thrombin activatable fibrinolysis inhibitor and clot lysis time in women with recurrent miscarriage associated with the antiphospholipid syndrome. |
| PubMedID- 25674114 | In the absence of any therapeutic intervention, only about 25% of these pregnancies results in live births.1 according to some authors thrombophilic markers are not the only criteria for the initiation of thromboprophylactic treatment.2,3 other investigators, however suggested not to treat unexplained miscarriage without evidenced antiphospholipid syndrome or inherited thrombophilia, with heparin or aspirin because of lack of evidence of any benefit and potential risks of therapy. |
| PubMedID- 20795446 | This retrospective review of hospital records analysed pregnancy outcome with 2 different treatments for women with recurrent miscarriage diagnosed with antiphospholipid syndrome in the index pregnancy. |
| PubMedID- 21792337 | Small-scale trials investigating the use of aspirin in the prevention of recurrent miscarriage in women without antiphospholipid syndrome have so far found little benefit;88 however, the findings regarding aggregation response to arachidonic acid lend support to reevaluating the benefit of aspirin in larger trials with a clearly defined cohort of individuals with recurrent miscarriage. |
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