PedAM
Pediatric Disease Annotations & Medicines
| Disease | anoxia |
| Phenotype | C1140680|ovarian cancer |
| Sentences | 2 |
| PubMedID- 26205780 | Two potentially novel biomarkers of hypoxia in ovarian cancer were selected – angiopoietin like protein 4 (angptl4, up-regulated in both a2780 and a2780cis in response to hypoxia exposure) and human epidermal growth factor receptor 3 (her3, up-regulated in a2780cis compared to a2780, and in hypoxic a2780 compared to normoxic a2780 while down-regulated in the a2780cis ‘hypoxic only’ response to cisplatin. |
| PubMedID- 24532538 | Although the actual structure of lc3a‐positive sls is unknown, it has been reported that the number of such sls is positively associated with markers of hypoxia in ovarian cancer (spowart et al., in press) and colorectal cancer (giatromanolaki et al., 2010). |
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