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PedAM

Pediatric Disease Annotations & Medicines




Disease anoxia
Phenotype C0235974|pancreatic cancer
Sentences 5
PubMedID- 24782785 hypoxia in pancreatic cancer also selects for cancer cell clones with phenotypic changes that confer a survival advantage and consequently enhance their aggressiveness and chemoresistance.
PubMedID- 24281216 hypoxia in pancreatic cancer has been reported to increase its malignant potential.
PubMedID- 21887310 Taken together, our data indicating changes in morphology, growth pattern, protein expression, drug resistance and invasion support the notion that hypoxia leads to emt in pancreatic cancer cells.
PubMedID- 24305593 High levels of hypoxia in pancreatic cancers can be detected intraoperatively with an oxygen microelectrode [23].
PubMedID- 26325106 This study establishes the feasibility to assess hypoxia in pancreatic cancer patients using pimonidazole, but questions the reliability of measurements made using a single tissue section.

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