PedAM
Pediatric Disease Annotations & Medicines
| Disease | anoxia |
| Phenotype | C0042373|vascular disease |
| Sentences | 12 |
| PubMedID- 23968588 | Obstructive sleep apnea is characterized by intermittent hypoxia (ih), and associated with cardiovascular diseases, such as stroke and heart failure. |
| PubMedID- 21941533 | Abundant evidence has demonstrated that oxidative stress is a key player in ischemia due to oxygen reperfusion injury following hypoxia, leading to both cardiovascular diseases and strokes [9, 10]. |
| PubMedID- 24478719 | Watershed areas of deep and periventricular white matter are particularly vulnerable to hypoperfusion and hypoxia, especially with age-related vascular disease and dysfunction (rowbotham and little, 1965; faraci and heistad, 1990; matsushita et al., 1994). |
| PubMedID- 21138564 | Beside the age - mediated pathogenetic mechanism, microvascular disease may lead to tissue hypoxia, resulting in production of oxygen free radicals, which, in turn, leads to overproduction of growth factors and cytokines [57-59]. |
| PubMedID- 26409337 | Background: sleep disorders and nocturnal hypoxia are common in patients with cerebrovascular disease. |
| PubMedID- 25530704 | Network-based association of hypoxia-responsive genes with cardiovascular diseases. |
| PubMedID- 23097656 | hypoxia is generally associated with cardiovascular diseases, and it elicits a variety of functional responses in cardiomyocytes, including cell proliferation, cell hypertrophy and cell death. |
| PubMedID- 24466084 | The ca1 subfield of the hippocampus is known to be particularly vulnerable to excitotoxicity resulting from hypoxia and ischemia associated with vascular disease [44], and an animal study using rat model of sivd showed substantially metabolic and histological neurodegeneration in this subfield [45]. |
| PubMedID- 23230237 | Obstructive sleep apnoea (osa) is common in the general population and increases the risk of motor vehicle accidents due to hypersomnolence from sleep disruption, and risk of cardiovascular diseases owing to repetitive hypoxia, sympathetic nervous system activation, and systemic inflammation. |
| PubMedID- 24476740 | The rationale behind the use of cell-based therapies—besides the presence of macro- and microvascular disease leading to ischemia and hypoxia or hyperglycemia, infection, and inflammatory reactions and so on—is the fact that cells in chronic wounds are phenotypically altered or senescent or both [10,11]. |
| PubMedID- 20671923 | These infections are rarely deadly but are considerably distressing because many patients often suffer of diabetes or vascular diseases with tissue hypoxia, other patients are immunosuppressed drugaddicts, or with concomitant hiv infection. |
| PubMedID- 26444711 | There is a search for rescue therapy against fetal origins of cardiovascular disease in pregnancy complicated by chronic fetal hypoxia, particularly following clinical diagnosis of fetal growth restriction (fgr). |
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