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PedAM

Pediatric Disease Annotations & Medicines




Disease anoxia
Phenotype C0040053|thrombosis
Sentences 6
PubMedID- 21959411 The pathogenesis of orn follows the "3hs theory" proposed by marx (j oral maxillofac surg 1983;41:283-288) in which radiation induces tissue injury by causing vessel thrombosis (hypovascularity), which leads to hypoxia, and results in cell death of the skin and the underlying structure of the bony element (hypocellularity) including the deep visceral structures.
PubMedID- 26084470 Vascular occlusion and intravascular thrombosis lead to tissue hypoxia in perivascular regions.
PubMedID- 20838435 It has been suggested that vascular pathology, including vascular endothelial apoptosis, vascular occlusion and thrombosis, initiates the development of central hypoxia and necrosis.
PubMedID- 22199040 High altitude can precipitate thrombosis because of hypobaric hypoxia and its effect on coagulation system.
PubMedID- 26236522 The pathogenesis of dmi may involve atherosclerotic occlusion, hypoxia-reperfusion injury, vasculitis with thrombosis, arterial embolism of small vessels, and a hypercoagulable state [2–7].
PubMedID- 26123634 Although altered perfusion may reduce oxygen delivery and impair energy production [136], vascular changes, that is, microvascular thrombosis, as the cause of hypoxia-like changes in ms have been questioned, since hypoxia-like changes have been observed in ms patients in the absence of vascular pathology [137].

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