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PedAM

Pediatric Disease Annotations & Medicines




Disease anoxia
Phenotype C0032914|preeclampsia
Sentences 4
PubMedID- 23817493 Gestational hypoxia induces preeclampsia-like symptoms via heightened endothelin-1 signaling in pregnant rats.
PubMedID- 24551035 Nets have been suggested to contribute to placental hypoxia in patients with preeclampsia [30]; however, the interplay between micro-debris, neutrophil activation and nets in successful human pregnancies remains to be determined.
PubMedID- 26352066 Objective: preeclampsia leads to chronic intrauterine hypoxia by interfering with placental blood supply.
PubMedID- 24877077 (1) elevation in the a2bar observed in preeclampsia may be associated with activation of hypoxia inducible factor 1 alpha (hif-1α) [56], since the a2bar promoter contains a functional binding site for hif-1 α [57], which promotes a2bar expression in huvec [22].

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