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PedAM

Pediatric Disease Annotations & Medicines




Disease anoxia
Phenotype C0032461|polycythemia
Sentences 4
PubMedID- 24251255 Chronic intrauterine hypoxia stimulates erythropoiesis leading to polycythemia in these iugr neonates at birth; however, this occurs at the cost of loss of the iron stores to fulfill the demands of increased erythropoiesis.
PubMedID- 24781045 Recently identified is a new syndrome consisting of multiple and recurrent pgls or pheos, somatostatinoma, and congenital polycythemia, due to somatic hypoxia-inducible factor 2alpha gene (hif2a) mutations.
PubMedID- 21712881 Patients with eisenmenger syndrome have polycythemia because of chronic hypoxia but our patient was anaemic and had thrombocytopenia because of thalassemia major.
PubMedID- 22983159 Because of endothelial dysfunction in lupus patients with ph, long-term hypoxia and hypercapnia lead to secondary polycythemia, hypercoagulability, stasis of the microcirculation, and then increasing risk of thrombosis and embolism.

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