PedAM
Pediatric Disease Annotations & Medicines
| Disease | anoxia |
| Phenotype | C0032051|placental insufficiency |
| Sentences | 9 |
| PubMedID- 22828032 | Prenatal utero-placental insufficiency with chronic fetal hypoxia can lead to foetal growth retardation with a redistribution of blood flow favouring the cerebral circulation and reducing mesenteric perfusion [2]. |
| PubMedID- 22748101 | Placental transfer of nicotine and carbon monoxide in tobacco smoke can induce placental hypoxia, leading to utero-placental insufficiency and inadequate delivery of o2 and nutrients to the developing fetus [282]. |
| PubMedID- 21331165 | The fetal syndrome includes fetal growth restriction, small-size-for-gestational-age (sga), reduced amniotic fluid, and placental insufficiency leading to fetal hypoxia and hypoperfusion. |
| PubMedID- 24282500 | Impaired placental perfusion due to placental insufficiency leads to placental hypoxia and a severely growth restricted fetus. |
| PubMedID- 22132338 | In humans, several pregnancy complications including placental insufficiency are associated with fetal hypoxia and metabolic acidosis. |
| PubMedID- 21908372 | Fetal death was attributed to placental insufficiency with subsequent hypoxia and amniotic fluid aspiration. |
| PubMedID- 24314237 | Chronic hypoxia arising from placental insufficiency can also cause severe fetal growth restriction (fgr). |
| PubMedID- 20981293 | Chronic hypoxia associated with placental insufficiency plays a key role in the etiology of intrauterine growth restriction (iugr). |
| PubMedID- 25330710 | At birth, hypoxia following placental insufficiency resulted in increased levels of lipid peroxidation, bcl-2-associated x protein mrna expression, and caspase-3 activity.30 (bcl-2-associated x protein is a mitochondrial-associated pro-apoptotic protein33 and caspase-3 is involved in dna fragmentation.34,35) these markers of apoptosis were not increased in placental insufficiency or hypoxia alone. |
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